Browsing by Author "Kaunas, Roland"
Now showing items 1-20 of 27
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Haskell, Andrew; Lee, Ryang-Hwa; Kaunas, Roland; Gregory, Carl (Don & Ellie Knauss Veteran Resource & Support Center; Texas A&M University. Library, 2023)Mesenchymal stem cells (MSCs) exhibit characteristics that make them ideal to treat a variety of disorders
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Smith, Rebecca (2014-01-14)Endothelial cell (EC) junctions are critical for angiogenesis, the sprouting and growth of new blood vessels from existing vessels. Sphingosine 1-phosphate (S1P) is a proangiogenic factor that potently stimulates sprouting, ...
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Xin, Shangjing (2019-11-13)Therapeutic cell delivery is a major strategy to stimulate the repair in tissue engineering and regenerative medicine. Efficacious cell therapies require a biomaterial carrier to retain injected cells in degenerated sites ...
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Rogers, Robert Eugene (2022-05-05)Bioreactor-mediated expansion of human mesenchymal stem cells (hMSCs) is a promising technique for the generation of hMSCs and their secreted products for immunoregulation therapies at scales required for use in the clinic. ...
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Jia, Wenkai (2021-07-30)The importance of tissue-specific microenvironments in achieving physiological cell and tissue functions has spurred the advancement of extracellular matrix (ECM) scaffolds for tissue engineering. Unlike defined scaffolds ...
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Sears, Candice Marie (2019-04-15)Extracellular matrix (hMatrix) derived from osteogenically enhanced mesenchymal stem cells (OEhMSCs) can be deposited onto scaffolds in a process referred to as “bioconditioning”. While bioconditioned gelatin scaffolds ...
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Leow, Wee Wen (2012-07-16)Extracellular microenvironment, including its components and biophysical parameters such as matrix structure and stiffness, is a crucial determinant of cellular function. There exists interdependency between cellular ...
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Shi, Jie (2021-07-05)The nonstructural protein 1 (NS1) of the 1918 Spanish influenza A virus hijacks N-terminal Src-homology 3 (nSH3) domain of host’s cellular CrkII with exceptionally high affinity through its proline-rich motif (PRM NS1). ...
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Horn, John David (2018-04-30)To mitigate the risk of intracranial aneurysm rupture, which can lead to severe debilitation or death, embolic devices (e.g., bare metal coils or polymeric open-celled foams) are often delivered via catheter to the aneurysm ...
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Tigner, Thomas Jamison (2023-08-02)Hydrogels are widely used as scaffolds in tissue engineering. Designing biocompatible hydrogel platforms requires consideration of fabrication techniques and routes of administration. Click chemistries facilitate crosslinking ...
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Wilson, Scott Andrew (2017-08-01)Three-dimensional (3D) printing is an emerging approach for rapid fabrication of complex tissue structures using cell-loaded bioinks. However, 3D bioprinting has hit a bottleneck in progress due to the lack of suitable ...
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Whitely Jr, Michael Edward (2018-07-30)A pressing need exists to develop an improved bone replacement to treat the millions of non-union fractures that occur each year as a result of severe trauma, tumor resection, spinal fusions, and joint replacements. Current ...
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The Direction of Stretch-Induced Cell and Stress Fiber Orientation Depends on Collagen Matrix Stress Tondon, Abhishek; Kaunas, Roland; Kumar, Sanjay (PloS One, 2014)
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A Dynamic Stochastic Model of Frequency-Dependent Stress Fiber Alignment Induced by Cyclic Stretch Hsu, Hui-Ju; Lee, Chin-Fu; Kaunas, Roland; Jaeger, Johannes (PloS One, 2009)
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Carrow, James Kenning (2018-08-03)Two-dimensional (2D) nanomaterials are an emerging class of biomaterials that have garnered unprecedented attention due to their unique atomically thin, layered, and well-defined structure. These nanomaterials, however, ...
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Dodson, Colin R (2014-10-02)An osteochondral defect is a joint injury characterized by the loss of cartilage along with a thin layer of bone beneath it. The cause of this condition is attributed to a number of factors, including repetitive trauma ...
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Mc Neill, Eoin (2019-11-29)Extracellular matrix (ECM) is a primary component of the osteogenic microenvironment, providing support for attachment, proliferation, and differentiation to facilitate bone growth and maintenance. Previously we have shown ...
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Mondragon, Eli (2020-07-13)Engineered bone graft designs have been largely inspired by adult bone despite significant deviation from the composition of anabolic bone. Highly osteogenic extracellular matrix (ECM) secreted by human mesenchymal stem ...
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Chimene, David Calvin (2019-12-12)Three-dimensional (3D) bioprinting is emerging as a promising method for rapid fabrication of biomimetic cell-laden constructs for tissue engineering using cell-containing hydrogels, called bioinks, that can be cross-linked ...
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Yazdani-Beioky, Shiva (2011-02-22)The study of mechanobiology and the cellular response to the mechanical environment plays a vital role in the understanding of the atherogenesis and the treatment of the disease state through interventions such as stent ...