Browsing by Author "Humphrey, Jay D."
Now showing items 1-20 of 23
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Dye, Wendy Watson (Texas A&M University, 2006-10-30)Muscular dystrophy is a disease characterized by skeletal muscle weakness and wasting, but little is known of alterations in the vascular system that occur with this disease. The culprit in many muscular dystrophies is a ...
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Taucer, Anne Irene (2009-05-15)Marfan syndrome, affecting approximately one out of every 5,000 people, is characterized by abnormal bone growth, ectopia lentis, and often-fatal aortic dilation and dissection. The root cause is a faulty extracellular ...
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Heistand, Mark Richard (Texas A&M University, 2005-11-01)Knowledge of the mechanics of the lens capsule is crucial for improving cataract surgery as well as understanding better the physiological role of the lens capsule in the process of accommodation. Previous research on the ...
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Pedrigi, Ryan M. (2010-01-16)The primary function of the lens capsule of the eye unfolds during the process of accommodation; wherein, tension imposed onto its equator is released, allowing the elastic capsule to mold the underlying lens nucleus and ...
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Hackney, Erin Kathleen (2011-02-22)Cerebral vasospasm following subarachnoid hemorrhage has high morbidity and mortality. Mathematical modeling of the progression of the condition provides insight to improve clinical treatment of patients post subarachnoid ...
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Valentin, Auturo III (2010-10-12)Arteries possess the ability to grow and remodel in response to sustained alterations in biomechanical loading, likely via mechanisms that are similarly involved in diverse arterial pathologies and responses to treatment. ...
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da Silva Soares, Joao Filipe (Texas A&M University, 2008-10-10)Percutaneous transluminal balloon angioplasty followed by drug-eluting stent implantation has been of great benefit in coronary applications, whereas in peripheral applications, success rates remain low. Analysis of healing ...
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Wu, Qiaofeng (2011-08-08)A detailed understanding of the corneal biomechanical response is an important prerequisite to understanding corneal diseases such as keratoconus and for placing the empirical equations used in refractive surgery on a ...
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Guo, Hong (2009-06-02)Mounting evidence suggests that the normal biomechanical state of arteries may include a nearly equibiaxial intramural stress, and that arteries tend to undergo rapid and dramatic remodeling when perturbed from this normal ...
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Meyer, Clark A. (2010-07-14)Abdominal aortic aneurysms (AAA) are an expansion in diameter of the abdominal aorta and their rupture is a leading cause of mortality. One of the treatments for AAA is the implantation of an endograft (also called a stent ...
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Hsu, Hui-Ju (2010-01-14)Arterial endothelial cells (ECs) are subjected to pulsatile strain due to pressure changes in the cardiac cycle and this may play a significant role in vascular function in health and disease. Further, ECs differentially ...
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Kotiya, Akhilesh A. (Texas A&M University, 2008-10-10)Characterization of multiaxial mechanical properties of cardiovascular soft tissue is essential in order to better understand their growth and remodeling in homeostatic conditions and in response to injury or pathological ...
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David, Fredegusto Guido (Texas A&M University, 2007-04-25)Changes in the mechanics of the lens capsule of the eye arising from alterations of its native configuration can lead to undesirable clinical results. One example is the surgical introduction of a hole into the lens capsule ...
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Mohan, Anand (Texas A&M University, 2006-10-30)Multiple interacting mechanisms control the formation and dissolution of clots to maintain blood in a state of delicate balance. In addition to a myriad of biochemical reactions, rheological factors also play a crucial ...
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Parameterization of the size and shape of intracranial saccular aneurysms using Legendre polynomials Farley, Cory Wayne (Texas A&M University, 2005-02-17)Currently, size is used as the predetermining factor to judge whether a saccular aneurysm is likely to rupture. Recent studies of the nonlinear mechanics of saccular aneurysms suggest that it is unlikely that they enlarge ...
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Hu, Jin-Jia (Texas A&M University, 2007-04-25)Hypertension is a risk factor for many cardiovascular and cerebrovascular diseases such as atherosclerosis and stroke. It is therefore important to understand the effect of hypertension on temporal growth and remodeling ...
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Baltzer, Wendy Irene (Texas A&M University, 2005-02-17)Vascular reactivity to vasopressin and phenylephrine is potentiated by constrictor prostanoids (CP) in normotensive female (F) but not male (M) rat aorta and CP function is estrogen-dependent. This study investigated the ...
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Timmins, Lucas Howard (2011-08-08)Vascular stents have become a standard for treating atherosclerosis due to distinct advantages in trauma and cost with other surgical techniques. Unfortunately, the therapy is hindered by the risk of a new blockage (termed ...
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Xu, Hai (2012-10-19)Morphology change analysis of aorta images acquired from biological experiments plays a critical role in exploring the relationship between lamina thickness (LT), interlamellar distance (ILD) and fragmentation (furcation ...
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Wells, Paul B. (Texas A&M University, 2005-08-29)Clinical thermal therapies are widespread and gaining in appeal due to improved technology of heating devices and promising results. Outcomes of thermal treatment are often unpredictable and suboptimal, however, due in ...