Browsing by Author "Abbott, Louise C."
Now showing items 1-13 of 13
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Serpedin, Nesrin (Texas A&M University, 2004-09-30)The leaner mouse carries an autosomal recessive mutation in the α1A subunit of neuronal P/Q-type voltage gated calcium ion channels. Due to this mutation, the leaner mouse exhibits severe ataxia, absence seizures and ...
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Murawski, Emily M. (2010-07-14)Due to two different mutations in the gene that encodes the a1A subunit of voltage-activated CaV 2.1 calcium ion channels, the compound heterozygous tottering/leaner (tg/tgla) mouse exhibits numerous neurological deficits. ...
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Liu, Xuhong (Texas A&M University, 2007-04-25)Chronic exposure to manganese (Mn) causes the neurodegenerative movement disorder, manganism. A mouse model was developed to elucidate mechanisms involved in the etiology and progression of injury. Twelve-week old female ...
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Thuett, Kerry A. (2010-10-12)It is impossible to remove methylmercury (MeHg) from biological systems because MeHg is found throughout our environment in many fresh and salt water fish. The consumption of fish is important to human nutrition and health. ...
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Huang, Pei-San (2012-07-16)Nicotine, the major psychoactive ingredient of tobacco smoke, underlies numerous effects by activating neuronal nicotinic acetylcholine receptors. Both in vitro and in vivo studies suggest that nicotine is neuroprotective ...
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Koh, Wonryull (2009-05-15)This dissertation studies two problems related to geometric representation of neuroanatomical data: (i) spatial representation and organization of individual neurons, and (ii) reconstruction of three-dimensional neuroanatomical ...
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Shi, Liheng; Ko, Michael L.; Abbott, Louise C.; Ko, Gladys Y. -P.; Spafford, J. David (PloS One, 2012)
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Rodriguez, Tiffany M. (2010-07-14)A number of movements produced in everyday life require not only coordination of joints within a limb, but also coordination between one or more limbs. The aim of this dissertation was to examine the influence of biomechanical ...
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Waters, Paulette Francesca (Texas A&M University, 2004-09-30)Molecular and in vitro comparisons were performed using two isolates of Encephalitozoon hellem, one from an avian host and one from a human host, and one isolate of Encephalitozoon cuniculi from a rabbit. The molecular ...
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Bawa, Bhupinder (2009-05-15)Mutations of the α1A subunit of CaV 2.1 voltage gated calcium (VGCC) channels are responsible for several inherited disorders affecting humans, including familial hemiplegic migraine, episodic ataxia type and spinocerebellar ...
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El-Sayed, Ahmed Kamel; Zhang, Zhentao; Zhang, Lei; Liu, Zhiyong; Abbott, Louise C.; Zhang, Yani; Li, Bichun; Delihas, Nicholas (International Journal of Molecular Sciences, 2014)
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Yang, Huei-Fang (2012-10-19)The goal of fully decoding how the brain works requires a detailed wiring diagram of the brain network that reveals the complete connectivity matrix. Recent advances in high-throughput 3D electron microscopy (EM) image ...
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Richardson, Jarret Keith (2013-07-29)The electrical synapse was first described over 50 years ago. Since that time appreciation of its complexity and importance has grown, including the hypothesis that early transient formation of these synapses is important ...