Browsing by Author "Phillips, Timothy D."
Now showing items 21-40 of 42
-
Pangilinan, Norma Cabanos (Texas A&M University. Libraries, 1990)The metabolism of xanthotoxin, a naturally-occurring furanocoumarin photosensitizer, was studied in laying hens and lactating goats treated with a single oral dose equivalent to 10 mg xanthotoxin/kg of body weight. Within ...
-
Taylor, John Floyd (2012-02-14)Arsenic in drinking water is a problem in many developing nations such as Taiwan and Bangladesh. Currently, no oral binding agent exists for the mitigation of arsenic toxicity. The goals of this research were to 1) screen ...
-
Epps, Sharon V. R.; Harvey, Roger B.; Hume, Michael E.; Phillips, Timothy D.; Anderson, Robin C.; Nisbet, David J. (International Journal of Environmental Research and Public Health, 2013)
-
Abdel Rahim, Ma'en Ahmad (Texas A&M University, 2004-09-30)Sequence-specific small interfering RNA (siRNA) duplexes can be used for gene silencing in mammalian cells and as mechanistic probes for determining gene function. Transfection of siRNA for specificity protein 1 (Sp1) in ...
-
Howie, Laura Elizabeth (Texas A&M University. Libraries, 1992)The role of the aryl hydrocarbon (Ah) receptor in mediating the immunotoxic effects of several polychlorinated diphenyl ethers (PCDEs), polychlorinated biphenyls (PCBs), and alkyl-substituted polychlorinated dibenzofurans ...
-
Improvement of Feed and Nutrient Security for Sulfur and Fumonisin in Texas Feedlot Cattle Rations Brown, Ashli A (2023-07-25)Texas dominates cattle production nationwide, providing the largest scale of producers and industrial environments. Chemical toxins and contaminants in feed can cause unexpected foodborne illnesses and livestock deaths, ...
-
Zacharewski, Timothy Richard (Texas A&M University. Libraries, 1990)2,3,7,8-Tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) and related compounds elicit a broad range of biochemical and toxic responses. One aspect of this dissertation was to assess the utility of an in vitro induction bioassay ...
-
Yao, Cheng Catsby (Texas A&M University. Libraries, 1989)Halogenated aryl hydrocarbon(HAH)-induced porphyria is caused by alteration of porphyrin metabolism and results in the accumulation of hepatic and urinary porphyrins. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (75 μg/kg) caused ...
-
Stalder, James William (Texas A&M University. Libraries, 1991)Influence of pH, salt, phosphate, cooking temperature, muscle variation, carcass sex and maturity on lactate dehydrogenase (LDH, E.C. 1.1.1.27) activity in bovine tissue slurries was investigated. LDH activity declined ...
-
Petrescu, Anca Daniela (Texas A&M University, 2004-09-30)Cholesterol and fatty acyl-coenzymeA thioesters are signalling molecules with role in regulation of genes involved in lipid and glucose transport and metabolism. The studies described herein focused on three proteins that ...
-
Lee, Jeong Eun (Texas A&M University, 2006-04-12)In MCF7 and T47D cells cotreated with 1 nM 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) plus 0.1-10 μM 3Â,4Â-dimethoxy flavone (DMF), there was a concentration-dependent decrease in the TCDD-induced ethoxyresorufin ...
-
Vanderlaag, Kathryn Elisabeth (2009-05-15)One in 8 women will be diagnosed with breast cancer in the United States and estrogen receptor (ER) status largely influences the type and subsequent success of treatment employed. Although ER-positive breast cancer can ...
-
Lee, Wan-Ru (2009-05-15)The estrogen receptor (ER) is a ligand-activated transcription factor that regulates gene expression. The classical mechanisms of nuclear ER action include ligand-induced dimerization of ER which binds estrogen responsive ...
-
Chen, Chien-Cheng (2009-06-02)Estrogen receptor (ER) acts as a ligand-activated transcription factor that regulates the expression of genes. The genomic mechanisms of ER action include ligand-induced dimerization of ER which binds estrogen responsive ...
-
Dash, Bhagirathi (Texas A&M University, 2007-04-25)In this research, important stress and redox regulatory genes present in Hydra vulgaris were isolated and characterized to facilitate our understanding of the evolution and mechanisms of stress response. H. vulgaris heat ...
-
Jutooru, Indira Devi (2011-08-08)Methyl 2-cyano-3,11-dioxo-18b-olean-1,12-dien-30-oate (CDODA-Me) is a synthetic triterpenoid that inhibits growth of Panc1 and Panc28 pancreatic cancer cell lines and activates peroxisome proliferator-activated receptor B ...
-
Kamps, Carol Ann (Texas A&M University. Libraries, 1989)The mechanism by which cytochrome P-450IA1 gene expression is induced by polycyclic aromatic hydrocarbons and various polychlorinated dibenzo-p-dioxins involves an intracellular protein known as the Ah receptor. Within the ...
-
Laffin, Brian Edward (2009-05-15)Virtually all signaling pathways that play key roles in development such as the transfroming growth factor (TGF)-beta, notch, and wnt pathways also influence tumor formation, implying that cancer is in a sense development ...
-
Zhang, Shu (2009-05-15)Insulin-like growth factor-I (IGF-I) is a mitogenic polypeptide that induces proliferation and activation of kinase pathways in MCF-7 breast cancer cells. The role of estrogen receptor α (ERα) in mediating responses induced ...
-
Afriyie-Gyawu, Evans (Texas A&M University, 2006-04-12)It is well documented that aflatoxin contamination in foods presents significant economic and public health burdens worldwide. Aflatoxins, particularly aflatoxin B1 (AFB1), have been implicated in the etiology of disease and ...