Browsing by Author "Datta, Sumana"
Now showing items 21-27 of 27
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Clarke, Douglas Nelson (2012-02-14)Stroke is the leading cause of long term disability and the third leading cause of death in the United States. Perlecan plays a significant role in brain development by sequestering and delivering growth factors to ...
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Hernandez, Ana Maria (2009-05-15)Prostate cancer is the second leading cause of death from cancer in men in the United States. Most men will die of the advanced, metastatic form of the disease. Thus, treatment strategies targeting the metastatic form of ...
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Datta, Milton W; Hernandez, Ana Maria; Schlicht, Michael J; Kahler, Andrea J; DeGueme, Amy M; Dhir, Rajiv; Shah, Rajal B; Farach-Carson, Cindy; Barrett, Andrea; Datta, Sumana (Molecular Cancer, 2006)
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Lindner, Jonathan Ryan (2012-02-14)Developmental signaling pathways have many diverse roles throughout the life of an organism. The proper regulation of these pathways is essential for normal development, and misregulation can lead to diseases such as cancer. ...
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Ferguson, Brent Wade (2012-02-14)Heparan sulfate proteoglycans modulate many of the growth factor pathways that drive prostate cancer progression. Prior to being secreted into the extracellular matrix, the covalently attached HS chains are modified by ...
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Repnikova, Elena Aleksandrovna (2010-10-12)The sialyltransferase family is a group of enzymes that transfer sialic acid from donor CMP-Neu5Ac onto suitable carbohydrate chains of glycoproteins and glycolipids. In vertebrates, sialylation is implicated in many ...
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O'Brien, Erin L. (2010-07-14)This research aims to elucidate possible genes that affect transcriptional fidelity of RNA polymerase II (pol II) and quantify these affects in vivo. The main focus of this project is the small nonessential subunit of RNA ...