Browsing by Author "Chapkin, Robert S"
Now showing items 21-29 of 29
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Allen, Marilyn Jean (2014-05-29)CD4^(+) effector T cell subsets (e.g., Th1, Th17) are implicated in autoimmune and inflammatory disorders such as multiple sclerosis, psoriasis and rheumatoid arthritis. For optimal activation, IL-6 induces Th17 polarization ...
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Jia, Qian 1980- (2011-07-30)Bioactive food components containing n-3 polyunsaturated fatty acids (PUFA) and curcumin modulate multiple determinants that link inflammation to cancer initiation and progression. In this dissertation, both transgenic and ...
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Knight, Jason Matthew (2015-05-04)Predictive modeling of the dynamic, multivariate, non-linear, stochastic systems of biology is a difficult enterprise. High throughput measurement techniques are enabling new approaches to computational biology, but the ...
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Baker, Charli D (2017-05-01)The mitochondrial respiratory chain (MRC) consists of four large protein complexes that catalyze redox reactions driving cellular energy production. These complexes assemble into supra-molecular structures called supercomplexes ...
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Fuentes, Natividad R (2017-12-14)Approximately 30-50% of colorectal cancers contain KRas mutations, which confer resistance to standard therapy. A diet high in long-chain n-3 polyunsaturated fatty acids (n-3 PUFA) is generally considered chemoprotective ...
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Turk, Harmony 1985- (2012-08-30)The epidermal growth factor receptor (EGFR) is a transmembrane receptor tyrosine kinase integral in regulating cell growth, survival, and migration. EGFR signaling, which is dependent on localization of the receptor within ...
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Garcia Villatoro, Erika Leonor (2021-06-18)Functioning as both a boundary and gatekeepers between the external environment and internal tissues, intestinal epithelial cells (IECs) play a significant role in overall gut homeostasis. Dysfunction of the colonic mucosal ...
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Seidel, Derek Vaughn (2019-01-02)Alterations in gut microbiota and metabolome occur during colon carcinogenesis and metabolic syndrome, but these changes may be reduced by exposure to bioactive compounds in foods. We hypothesized that bioactive compound-rich ...
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Leyk Williams, Malgorzata (Texas A&M University, 2006-04-12)Intestinal tract cancer is one of the more common cancers in the United States. While in some individuals a genetic component causes the cancer, the rate of cancer in the remainder of the population is believed to be ...