Browsing by Author "Zhang, Xiuren"
Now showing items 1-20 of 22
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Wang, Yu (2016-01-14)AGO4, one of the ten AGO proteins in Arabidopsis, is involved in gene silencing at transcriptional level. The general objective of this research is to understand whether AGO4 protein plays a defense role against Myzus ...
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Xu, Hengyi (2015-05-13)In eukaryotes the ends of chromosomes are constituted by nucleoprotein complexes termed telomeres. Telomeres represses a DNA damage response and, more importantly, facilitate the maintenance of the terminal DNA sequence ...
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Su, Dongyin (2018-06-01)The Sucrose non-fermenting related kinase 1 (SnRK1) complex is a hetero trimer found in plants consisting of a catalytic a-subunit and regulatory b and g subunits. The SnRK1 complex can regulate a variety of metabolic ...
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Cifuentes-Rojas, Catherine (2012-02-14)Telomerase is a highly regulated ribonucleoprotein complex that stabilizes eukaryotic genomes by replenishing telomeric repeats on chromosome ends. Defects in telomerase RNP components involving the catalytic subunit TERT ...
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Sun, Di (2021-01-11)Posttranscriptional gene silencing (PTGS) involves two kinds of small non-coding regulatory RNAs, miRNA and small interfering RNA (siRNA) that regulate gene expression in diverse biological processes in eukaryotic organisms. ...
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Kumar, Vikas (2016-04-25)Trypanosoma brucei requires extensive remodeling of its mitochondrial gene expression during different stages of its life cycle. RNA editing is one of the vital processes for these mitochondrial changes. This process ...
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Hu, Fuqu (2014-08-13)Argonautes (AGOs) are central components in RNA-induced gene silencing complexes (RISCs) and control almost all aspects of developmental processes in eukaryotes. Study on AGO proteins not only elucidates the fundamental ...
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Functions of Arabidopsis C-terminal Domain Phosphatase-like 4 in Global Transcriptional Regulation Fukudome, Akihito (2017-05-02)Phosphoregulation of the carboxyl-terminal domain of RNA polymerase II largest subunit (pol II-CTD) couples transcription and co-transcriptional modification of nascent RNA. Although the molecular mechanisms have been ...
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Castillo-González, Claudia; Liu, Xiuying; Huang, Changjun; Zhao, Changjiang; Ma, Zeyang; Hu, Tao; Sun, Feng; Zhou, Yijun; Zhou, Xueping; Wang, Xiu-Jie; Zhang, Xiuren; Weigel, Detlef (ELife, 2015)
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Wood, Jeremy Lee (2019-04-19)Combating the persistent threat and low therapeutic success of treating multidrug-resistant Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, demands a worldwide effort to discover and develop new ...
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Castillo Gonzalez, Claudia Marcela (2017-07-21)The hosts-virus arms race reaches the epigenetic level, where silencing of viral chromatin can serve as an innate defense mechanism to restrict invading DNA viruses. However, viruses can code for suppressor proteins to ...
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Lei, Jia Xin (2014-11-26)Aphid, a specialized phloem sap-feeding insect, is one of the major pests of a number of economic important crops, including soybean, cotton, and maize. Aphid can have devastating effects on the crop production by limiting ...
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Guthrie, Aaron S 1987- (2012-12-05)Isothiocyanates (ITCs) are phytochemicals highly expressed in cruciferous vegetables and these compounds are associated with the decreased incidence of cancers in populations consuming high levels of cruciferous vegetables. ...
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Zhang, Zhonghui; Hu, Fuqu; Min Woo Sung; Shu, Chang; Claudia Castillo-González; Koiwa, Hisashi; Tang, Guiliang; Dickman, Martin; Li, Pingwei; Zhang, Xiuren (ELife, 2017)
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Hernandez, Alfredo J. (2012-02-14)RNA editing in trypanosomes is the post-transcriptional insertion or deletion of uridylates at specific sites in mitochondrial mRNAs. This process is catalyzed by a multienzyme, multisubunit complex through a series of ...
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Guan, Jingwen (2019-11-11)Cellular decision-making is a ubiquitous biological process among all organisms, from simple viruses to complex mammals, occurring when living systems process signals received from the environment and then make appropriate ...
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Lu, Cheng (2012-10-19)RIG-I-like receptors (RLRs), RIG-I, MDA5, and LGP2, are a family of innate immune receptors that recognize viral RNA in the cytoplasm and initiate antiviral responses including the induction of type I interferons and other ...
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McLachlan, Juanita (2013-04-29)Two Tomato bushy stunt virus (TBSV) proteins, P19 and P22, have been found to interact with the Nicotiana benthamiana host proteins Hin19 and HFi22 in yeast two,hybrid assays. To determine functional roles of these interacting ...
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Renfrew, Kyle Brayton (2014-11-06)Telomeres are the physical ends of eukaryotic chromosomes. Because chromosome ends resemble double–strand breaks, telomere binding proteins mask telomeres from DNA damage response machinery. Consequently, telomere protection ...
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Meehan, Joshua Everett (2023-05-11)T. brucei is a protozoan parasite which is the causative agent of African Sleeping Sickness. It undergoes a complex lifecycle as it switches between its insect vector and mammalian hosts. Mitochondrial mRNAs are genomically ...