| dc.contributor.advisor | Womack, James E. | |
| dc.creator | Nettleton, Mignon Y. | |
| dc.date.accessioned | 2022-06-30T16:12:03Z | |
| dc.date.available | 2022-06-30T16:12:03Z | |
| dc.date.issued | 1983 | |
| dc.identifier.uri | https://hdl.handle.net/1969.1/CAPSTONE-NettletonM_1983 | |
| dc.description | Program year: 1982-1983 | en |
| dc.description | Digitized from print original stored in HDR | en |
| dc.description.abstract | The cattle genome contains a gene for vesicular stomatitis virus (VSV) sensitivity, possibly coding for a VSV receptor molecule. This was demonstrated by a VSV challenge to cattle-hamster hybrid clones segregating cattle chromosomes. Linkage of this gene to cattle genes coding for different enzymes was not established with the small mumber of clones examined in this study.
The gene for β-interferon receptor (IfRec) was found to be linked to the superoxide dismutase-1 (SOD-1) locus, with only one discrepancy in the nine clones examined. Since this linkage has been reported in humans on chromosome 21 and mice on chromosome 16, its conservation in cattle is interesting from both evolutionary and medical perspectives. | en |
| dc.format.extent | 19 pages | en |
| dc.format.medium | electronic | en |
| dc.format.mimetype | application/pdf | |
| dc.subject | vesicular stomatitis virus | en |
| dc.subject | cattle hybrid clones | en |
| dc.subject | β-interferon receptor | en |
| dc.subject | cattle genetics | en |
| dc.title | Mapping Bovine Genes for Viral and β-interferon Sensitivity in Somatic Cell Hybrids | en |
| dc.type | Thesis | en |
| thesis.degree.department | Veterinary Pathology | en |
| thesis.degree.grantor | University Undergraduate Fellows | en |
| thesis.degree.level | Undergraduate | en |
| dc.type.material | text | en |
