| dc.contributor.advisor | Lewis, R. W. | |
| dc.creator | Reza, David | |
| dc.date.accessioned | 2022-04-04T13:44:22Z | |
| dc.date.available | 2022-04-04T13:44:22Z | |
| dc.date.issued | 1977 | |
| dc.identifier.uri | https://hdl.handle.net/1969.1/CAPSTONE-KiblerA_1998 | |
| dc.description | Program year: 1976/1977 | en |
| dc.description | Digitized from print original stored in HDR | en |
| dc.description.abstract | This research proposal was presented in order to determine the metabolic fate of 6-mercaptopurine (6-MP) and its bismuth and palladium complexes. This was done by manner of determining the levels of the metals, bismuth and palladium, in the blood serum of rats that were intraperitoneally administered 6-MP, the bismuth complex of 6-MP, and the palladium complex of 6-MP. Two conclusions were made as a result of this study; (1) free 6-MP proved to be more toxic than either of the metallo-complexes, and (2) the levels of bismuth and palladium in all three treatment groups were no different from those in the control group indicating that the compounds/greatest therapeutic effects are not in the circulatory system of the mammals. | en |
| dc.format.extent | 16 pages | en |
| dc.format.medium | electronic | en |
| dc.format.mimetype | application/pdf | |
| dc.subject | 6-mercaptopurine | en |
| dc.subject | bismuth | en |
| dc.subject | palladium | en |
| dc.subject | blood serum | en |
| dc.subject | toxicity | en |
| dc.title | The Metabolic Fate Of 6-Mercaptopurine And Its Bismuth And Palladium Complexes | en |
| dc.title.alternative | THE METABOLIC FATE OF 6-MERCAPTOPURINE AND ITS BISMUTH AND PALLADIUM COMPLEXES | en |
| dc.type | Thesis | en |
| thesis.degree.department | Biochemistry | en |
| thesis.degree.grantor | University Undergraduate Fellow | en |
| thesis.degree.level | Undergraduate | en |
| dc.type.material | text | en |
