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G Protein-coupled Estrogen receptor is activated by G-1 which induces a signaling cascade that inhibits breast cancer cell proliferation
(2012-06-08)
Breast cancer is the most common cancer in women and is predominantly estrogen dependent [1]. About 1 in 8 women in the United States (12%) will develop invasive breast cancer over the course of her lifetime. Failure in ...
Characterizing Epithelial-Mesenchymal-Transition (EMT)-Like Behavior in Breast Cancer Cells in a Tissue Engineering Co-Culture Model
(2020-04-13)
Tissue engineered 3D cell culture models have shown promise investigating the influence of the tumor microenvironment on cancer cell behavior. Synthetic hydrogels, such as those made from poly(ethylene glycol) (PEG), can ...