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Now showing items 1321-1330 of 3009
Identifying Nuclear Receptor Ligands through Sequence-Based Deep Learning
(2020-04-16)
This project focuses on developing machine learning methods to predict protein-ligand interactions. The unique proteins under study are nuclear receptors (NRs), which regulate hormone-triggered gene transcription and are ...
Single-Electron Resolution Phonon-Mediated Detectors: Progress and Applications
(2020-04-23)
Many astrophysical observations indicate that nonbaryonic dark matter makes up around 85% of the total mass content of the Universe. The SuperCDMS experiment represents one of many concerted efforts around the world to ...
Perceptions of Teaching Culturally Relevant Math Lessons in a Simulated Virtual Classroom: A Case Study of Preservice Teachers
(2020-04-15)
The Knowledge for Algebra Teaching for Equity (KATE) research team endeavored to redesign a mathematics problem solving course to provide opportunities for preservice teachers (PSTs) to practice creating and implementing ...
Surface-Water Connectivity Within a Coastal Lowland Riverine Landscape
(2020-02-27)
Lowland riverine landscapes regularly flood and create complex spatial patterns of inundation that create surface-water connections between landscape patches that allow energy, matter, biota, and information to be exchanged. ...
Adaptive and Orbital Element Methods for Conjunction Analysis
(2020-01-25)
Collisions between Earth orbiting satellites and debris have been a topic of growing concern among satellite operators and governments for many years. At the heart of preventing collisions, which have been observed to have ...
Flame Retardant/Thermal Protection Nanocoatings: Meeting Industrial Challenges of Layer-by-Layer Assembly
(2020-03-04)
Polymeric materials are widely used in every day applications, despite being highly flammable. In an effort to decrease the flammability of these materials, environmentally-benign nanocoatings have been deposited on common ...
The Brucella Effector Grhg1 Reprograms the Host N-Glycome to Sustain Infection
(2020-02-17)
The intracellular bacterium Brucella is a globally distributed pathogen that causes brucellosis, a disease of wildlife, domesticated animals, and humans. The virB Type IV secretion system (virB-T4SS) plays an essential ...
Process Integration and Optimization with Reliability, Safety, and Cost Analyses
(2020-04-23)
As the global population reached more than 7.7 billion, the needs for better living conditions and industrialization have grown rapidly all over the world. As the result, the consumption of natural resources has risen ...
Mesenchymal Phenotype of Cholangiocytes Plays an Integral Role in the Regulation of Biliary Senescence and Liver Fibrosis in Cholestatic Liver Diseases
(2020-03-17)
Cholangiocytes are the epithelial cells lining the bile ducts in the liver and the target of cholestatic liver diseases, such as primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC). Cholangiopathies ...
Modeling and Simulation of Viscoelastic Soft Materials for Soft Robotic Applications
(2020-04-16)
This study presents numerical simulations of deformations and shape changes in soft and flexible systems suitable for soft robotics structures. The compliant nature of soft materials, such as silicone elastomer, rubber and ...