Browsing Colleges and Schools by Department "Biomedical Engineering"
Now showing items 21-40 of 331
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(2015-12-07)Extracellular matrix is a complex network of molecules that accomplishes various roles within each tissue. The mechanical properties and biochemical composition of the extracellular matrix vary considerably across tissues. ...
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(2015-12-02)Bone is the second most transplanted organ following blood, and significant advances have been made in developing synthetic bone graft substitutes and scaffolds. However, there remains a critical need for osteoinductive ...
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(2018-11-08)Tissue engineering strategies incorporate cells and bioactive cues within a synthetic scaffold to mimic the biophysical and biochemical properties of native tissue to regenerate or repair damaged tissues and organs. A major ...
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(2010-10-12)Commonly used thermoplastic biodegradable polymers are generally brittle and lack appreciable elasticity at physiological temperature and thereby fail to mimic the elastic nature of many human soft tissues such as blood ...
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(2020-11-19)Embolic coils have become a valuable tool for occluding brain aneurysms to reduce the occurrence of hemorrhagic strokes and the associated high mortality and morbidity rates, but this strategy is still limited by high rates ...
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(2019-07-25)Growing interest in implantable electronics (neuro-integrated prostheses, bionic eyes, etc.) has identified the need to establish functional interfaces between traditional solid-state electronics and biomolecular events ...
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(2009-05-15)Marfan syndrome, affecting approximately one out of every 5,000 people, is characterized by abnormal bone growth, ectopia lentis, and often-fatal aortic dilation and dissection. The root cause is a faulty extracellular ...
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(Texas A&M University, 2005-11-01)Knowledge of the mechanics of the lens capsule is crucial for improving cataract surgery as well as understanding better the physiological role of the lens capsule in the process of accommodation. Previous research on the ...
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(2010-01-16)The primary function of the lens capsule of the eye unfolds during the process of accommodation; wherein, tension imposed onto its equator is released, allowing the elastic capsule to mold the underlying lens nucleus and ...
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(2014-03-28)Each year, millions of patients undergo reconstructive surgery to treat injuries caused by trauma, deformities, or tumor resection. Repair of these defects often requires the use of tissue grafts to promote healing. Current ...
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(Texas A&M University, 2006-08-16)Collecting microlymphatics play a vital role in promoting lymph flow from the initial lymphatics in the interstitial spaces to the large transport lymph ducts. In most tissues, the primary mechanism for producing this flow ...
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(2019-06-03)The overall physiological function of a tissue or organ is closely related to its mechanical properties. These properties may change during many normal physiological processes or as part of healthy adaptations to altered ...
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(2014-05-01)The shape memory polymer (SMP) is one type of smart material with shape memory effect. SMP’s recovery can be actuated by external energy, such as heat. However, traditional direct heating limits potential applications of ...
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(2021-07-30)The importance of tissue-specific microenvironments in achieving physiological cell and tissue functions has spurred the advancement of extracellular matrix (ECM) scaffolds for tissue engineering. Unlike defined scaffolds ...
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(2019-04-15)Extracellular matrix (hMatrix) derived from osteogenically enhanced mesenchymal stem cells (OEhMSCs) can be deposited onto scaffolds in a process referred to as “bioconditioning”. While bioconditioned gelatin scaffolds ...
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(2012-07-16)Extracellular microenvironment, including its components and biophysical parameters such as matrix structure and stiffness, is a crucial determinant of cellular function. There exists interdependency between cellular ...
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(2009-05-15)Elasticity of α-helices and coiled coils have often been described by a linear response to local bending with bending stiffness (Kb) and persistence length (Lp) describing their flexibility. However, we observed that the ...
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(2015-04-15)Reticulation, the process of opening and removing cell membranes from shape memory polymer (SMP) foam, is an important processing technique to improve the permeability of SMP foam for utilization in several biomedical ...
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Characterization of Engineered Tissue by Multimodal Optical Imaging and Biaxial Mechanical Testing (2014-04-28)To better understand the relationships between mechanical stimuli and cellular responses, we developed a 3D tissue bioreactor coupling to both a biaxial mechanical testing platform and a stage for multimodal microscopy. ...
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(2015-08-13)An optical biosensor for lactate detection is described. By encapsulating enzymes and phosphorescent oxygen sensing molecules within permeable hydrogel materials, a lactate-sensitive change in emission lifetimes was achieved. ...