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Use of bacterial beta-lactamase for in vitro diagnostics and in vivo imaging, diagnostics and therapeutics
(United States. Patent and Trademark Office, 2016-09-13)
Provided herein are assays and in vitro methods to determine susceptibility to a drug effective against a pathogenic bacteria, for example, a pathogenic Mycobacteria, that has a beta-lactamase activity. An excitation ...
β-lactamase substrates and methods of their use for the diagnosis of tuberculosis
(United States. Patent and Trademark Office, 2017-06-13)
β-Lactamase substrates and methods for using the substrates to detect β-lactamase diagnose tuberculosis.
2,7-disubstituted cephalosporin derivatives as beta-lactamase substrates and methods for their use for the diagnosis of tuberculosis
(United States. Patent and Trademark Office, 2017-12-05)
β-Lactamase substrates and methods for using the substrates to detect β-lactamase and to diagnose tuberculosis.
2,7-disubstituted cephalosporin derivatives as β-lactamase substrates and methods for their use for the diagnosis of tuberculosis
(United States. Patent and Trademark Office, 2019-07-09)
β-Lactamase substrates and methods for using the substrates to detect β-lactamase and to diagnose tuberculosis.
Use of bacterial beta-lactamase for in vitro diagnostics and in vivo imaging, diagnostics and therapeutics
(United States. Patent and Trademark Office, 2015-09-22)
Provided herein are methods for detecting, quantifying, differentiating, diagnosing and imaging pathogenic bacteria or condition associated therewith using substrates for bacterial enzymes. Fluorescent, luminescent or ...