Compositions and methods of enhancing immune responses to enteric pathogens
Abstract
Vaccine vectors capable of eliciting an immune response to enteric bacteria and methods of using the same are provided. The vaccine vectors include a polynucleotide encoding a PAL polypeptide. The PAL polypeptide may be expressed on the surface of the vaccine vector. The vaccine vector may also include a second polypeptide encoding an immunostimulatory polypeptide such as a CD154 polypeptide or an HMGB1 polypeptide.
Subject
C07K 16/1232A61K 39/107
A61K 39/0258
A61K 39/0275
A61K 39/105
C12N 15/85
A61K 2039/53
A61K 2039/523
Y02A 50/30
C07K 2317/34
Collections
Citation
Bielke, Lisa; Layton, Sherryll; Hargis, Billy; Pumford, Neil R.; Faulkner, Olivia B.; Berghman, Luc; Abi-Ghanem, Daad (2021). Compositions and methods of enhancing immune responses to enteric pathogens. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /193354.