Compositions and methods for drug sensitization of parasites
Abstract
Compositions and methods for inhibiting and/or sensitizing or re-sensitizing a parasite to an antiparasitic drug are provided. The compositions can comprise a an arylphenoxypropionate derivative, an aryloxyphenoxyacetate derivative, an aryloxyphenylacetate derivative, one or more substituted quinols, or a pharmaceutically acceptable salt, hydrate, or prodrug thereof, or a combination thereof in an amount and formulation sufficient to sensitize the parasite to the drug, treating infection of a patient by a parasite with a drug, or to prevent symptomatic infection of a patient by a parasite with a drug.
Subject
A61K 31/44A61K 31/423
A61K 31/428
A61K 31/4439
A61K 31/454
A61K 31/496
A61K 31/498
A61K 31/501
A61K 31/5377
A61K 31/541
A61K 31/7036
A61P 33/02
A61K 31/427
A61K 31/5355
A61K 31/517
A61K 31/353
Y02A 50/30
Y02A 50/419
Y02A 50/423
Y02A 50/49
Y02A 50/411
02A 50/491
Y02A 50/421
Y02A 50/414
Y02A 50/409
Collections
Citation
Reddy, Manchi C. M.; Sacchettini, James C.; Zhou, Nian E.; McClutchen, Billy F. (2020). Compositions and methods for drug sensitization of parasites. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /188150.