Compositions and methods of enhancing immune responses to Eimeria
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Vaccines comprising TRAP polypeptides and Salmonella enteritidis vectors comprising TRAP polypeptides are provided. The vaccines may also include a CD154 polypeptide capable of binding to CD40. Also provided are methods of enhancing an immune response against Apicomplexan parasites and methods of reducing morbidity associated with infection with Apicomplexan parasites.
Bottje, Walter; Hargis, Billy; Berghman, Luc; Kwon, Young Min; Cole, Kimberly; Cox, Mandy; Layton, Sherryll; El-ashram, Saeed; Barta, John; Tellez, Guillermo (2018). Compositions and methods of enhancing immune responses to Eimeria. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from