Compositions and methods of enhancing immune responses
Abstract
Provided herein are Salmonella enteritidis 13A strains and compositions comprising these strains. Also provided are methods of enhancing an immune response against Influenza A and methods of reducing morbidity associated with an Influenza A infection. Methods of enhancing an immune response to a vaccine vector by expressing a polypeptide of CD154 capable of binding CD40 are also disclosed. Methods of developing a bacterial vaccine vector are disclosed. Methods of generating scarless site-specific mutations in a bacterium are also disclosed.
Subject
A61K 39/145A61K 39/0275
A61K 39/12
C12N 15/102
A61K 39/00
A61K 2039/523
A61K 2039/55516
A61K 2039/6031
C07H 21/04
C12N 2760/16134
Collections
Citation
Bottje, Walter; Hargis, Billy; Berghman, Luc; Kwon, Young Min; Cole, Kimberly; Cox, Mandy; Layton, Sherryll (2016). Compositions and methods of enhancing immune responses. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /177128.