In Vitro Verification of Shape Memory Polymer Vascular Occlusion Plug
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The objectives for the current in vitro experiments are to perform verification tests that demonstrate the safety and feasibility of a proposed vascular occlusion plugs (VOPs) and the validity of the device design criteria. Tests will be executed to monitor the following qualities: migration, working time, device friction, and particulate generation. Results from device testing provides positive conclusions regarding the feasibility of the VOP design for peripheral embolization. There was limited risk of unintended embolization due to device migration. Expansion rates provide sufficient time for a physician to deliver the device trough a standard catheter. Frictional forces during expansion in catheter do not prevent delivery. Devices do not fracture or generate particulates that may cause thromboembolisms. All of the measured characteristics will aid in the design and optimization of novel SMP-based peripheral embolization devices.
Diguette, Katelin (2016). In Vitro Verification of Shape Memory Polymer Vascular Occlusion Plug. Undergraduate Research Scholars Program. Available electronically from