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Multicomponent vaccines
(United States. Patent and Trademark Office, 2010-02-23)
Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies ...
Cross-reactive displacing antibodies from collagen-binding proteins and method of identification and use
(United States. Patent and Trademark Office, 2007-07-10)
Antibodies to the CNA protein and to other regions from the collagen binding domain, including domain CNA19, are provided, and antibodies produced in this manner have been shown to be cross reactive to both Staphylococcus ...
Multicomponent vaccines
(United States. Patent and Trademark Office, 2004-03-09)
Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies ...
Fibronectin binding protein compositions and methods of use
(United States. Patent and Trademark Office, 2006-10-31)
Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...
Treatment of Staphylococcus aureus infections utilizing antibodies that bind to fibronectin binding proteins
(United States. Patent and Trademark Office, 2012-07-03)
Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...
Multicomponent vaccines
(United States. Patent and Trademark Office, 2011-09-13)
Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies ...
Compositions And Use Of A Fibrinogen Binding Motif Present In EFB And COA For Therapeutics And Vaccines Against Staphylococcus Aureus
(United States. Patent and Trademark Office, 8/9/2022)
The present disclosure provides methods and composition including vaccines, monoclonal antibodies, polyclonal antibodies, chimeric molecule of an extracellular fibrinogen binding protein (Efb) and targeted agent delivery ...
Targeting Of Ligand Binding Sites In ClfA
(United States. Patent and Trademark Office, 9/20/2022)
The present invention provides methods and compositions to reduce binding of fibrinogen to the ClfA in a gram positive bacterial infections using monoclonal antibody, a polyclonal antibody, an antigen-binding antibody ...