Histology of Calcium Aluminate vs. Tricalcium Silicate in Pulpal and Periradicular Contact
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NeoMTA Plus (Avalon Biomed Inc., Bradenton, FL) is a tricalcium silicate material similar to the first MTA product, ProRoot MTA (Dentsply, Tulsa Dental, Tulsa, OK) but with improvements such as decreased setting time, increased ion release, increased water sorption and decreased porosity. Quick-Set2 (Avalon Biomed Inc., Bradenton, FL) is a newly formulated calcium aluminosilicate material that has a faster setting time, increased acid resistance and is non-discoloring. The purpose of this study was to compare healing of pulpal and periapical tissues after exposure to NeoMTA Plus and Quick-Set2 following pulpotomy, root canal and root-end surgery procedures. One hundred eight teeth (36 for each procedure) in 6 Beagle dogs were isolated, accessed and treated with pulpotomy, root canal or root-end surgery. The materials for pulpotomy and root-end surgery were mixed to a putty-like consistency and the materials for root canals were mixed to a sealer consistency. The dogs were sacrificed at 90 days and the teeth and surrounding tissues were prepared for histological evaluation. Eighty-five teeth were evaluated and scored histologically. Specific for each procedure, specimens were scored for inflammation, quality and thickness of dentin bridging, pulp tissue response, cementum and PDL formation and apical bone healing. Both materials displayed favorable healing at 90 days. The only significant difference was higher quality of dentin bridge formation in pulpotomies exposed to NeoMTA Plus. Quick-Set2 and NeoMTA Plus had similar effects on inflammation, dentin bridge formation, pulp response, PDL and cementum formation and apical tissue healing in dogs.
Walsh, Ryan Michael (2016). Histology of Calcium Aluminate vs. Tricalcium Silicate in Pulpal and Periradicular Contact. Master's thesis, Texas A & M University. Available electronically from