Search
Now showing items 1-10 of 20
Biosynthetic studies on vitamin B₁₂
(1987)
The role of folates in the enzymatic formation of the porphyrin macrocycles was investigated. Uroporphyrinogen III cosynthetase-free hydroxymethylbilane synthase from Rhodopseudomonas spheroides was incubated with the ...
The isomerization of gold(I) ylide dimers and the preparation and structure of the gold(II) ylide dimers containing ligands coordinated through sulfur
(1987)
The preparation of the asymmetric gold dimer, 2, [Au(CH₂)₂P(C₆H₅)(CH₃)]₂, was carried out using Li[C₆H₅)(CH₃)P(CH₂)₂] and (C₆H₅)₃PAuCl. The trans isomer was isolated as the predominant product. Isomerization of trans-2 to ...
Californium-252 plasma desorption mass analysis of proteins adsorbed on polymer and modified-polymer surfaces
(1987)
A new Cf-252 plasma desorption mass spectrometer has been built specifically for the analysis of large biomolecules. This mass spectrometer was used to investigate the interactions between proteins adsorbed onto polymer ...
Kinetic and crystallographic analysis of porcine pancreatic elastase-ligand interactions
(1987)
Elastase (EC 3.4.21.11) is normally involved in the degradation of elastin, and is believed to be the primary agent responsible for the induction of several degenerative connective tissue diseases. The primary subsite ...
The role of electron transfer reactions on the electrical properties of membranes
(1987)
The objectives of this dissertation is to develop a model which will describe the relationship between electron transfer across membrane/solution interfaces and ion transport across the membrane. This model should be ...
Transition metal hydrides : deprotonation of a cationic molybdenum hydride and studies of nickel (II) hydrides
(1987)
The acid-base properties of transition metal hydrides are of import to the understanding the nature of the metal-hydride bond. Some neutral transition metal hydrides behave as Bronsted acids, and cationic-metal hydrides ...
A total synthesis of (±)-sirenin and analogs for the biological study of sexual pheromone activity in Allomyces
(1987)
The synthesis and biological evaluation of structural analogs of the potent fungal (Allomyces) sex pheromone sirenin (1) is described. A new total synthesis of the pheromone itself is also presented. In addition, the ...
Enzymes in organic synthesis
(1987)
Several aspects of the use of enzymes as catalysts in organic synthesis have been explored. The stability of the enzyme glucose dehydrogenase useful in reduced nicotinamide cofactor (NAD(P)H) regeneration has been studied. ...
Insertion and oxidative addition reactions of anionic group 6 complexes
(1987)
The anionic group 6 alkyl and aryl complexes cis-RM(CO)₄L⁻ (where M = W or Cr; R = Me, Et, or Ph; L = CO, P(OMe)₃, or PMe₃) have been shown to perform insertion of CO₂, CO, and SO₂ into the metal-alkyl (-aryl) bond. The ...
Catalytic oxidative dimerization of methane
(1987)
The results of this research indicate that [M⁺O⁻] centers (M = Group IA ions) in Group IA/Group IIA oxides are responsible for the catalytic production of CH₃[superscript dot] radicals from CH₄ through hydrogen atom ...