Browsing by Subject "click chemistry"
Now showing items 1-7 of 7
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(2011-08-08)Shwachman Diamond syndrome is an autosomal recessive disease associated with pancreatic insufficiency, skeletal abnormalities, and bone marrow failure. The de Figueiredo lab has recently shown physical and genetic interactions ...
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(2016-02-09)Poly(ethylene glycol) (PEG) gels are step-growth hydrogel networks that can be formed using thiol-ene polymerization. Four-arm PEG monomers can be functionalized with norbornene and then crosslinked with matrix metalloproteinase ...
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(2019-11-21)Click chemistry reactions have become an important synthetic tool for fabrication of user-defined hydrogels consisting of poly(ethylene glycol) (PEG) and bioactive peptides/proteins for tissue engineering. In this work, ...
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(2018-11-12)For eukaryotes, DNA is maintained in the form of chromatin, which is comprised of millions of repeated nucleosomes. Each nucleosome is assembled by wrapping 147 base pairs (bp) of DNA around a histone octamer containing 2 ...
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(2012-11-13)The major directions of this dissertation involve (1) the syntheses and characterization of molecular polygons incorporating sp1hybridized carbon linkers and L2Pt corners (L2 = cis-1,3-diphosphine), (2) the development of ...
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(2022-01-12)Herein, the discovery and application of a novel class of supramolecular secondary interactions between the cycloaddition products of the inverse electron-demand Diels Alder (IEDDA) tetrazine-norbornene click reaction is ...
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(2015-11-18)Extracellular matrix elasticity has been shown to affect a variety of cellular properties. However, the effect it has on pathogen-host cell interaction has yet to be thoroughly evaluated. Furthering our understanding of ...