Browsing by Subject "bone"
Now showing items 1-20 of 24
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(2012-07-11)The effect of partial gravity (G) (as on the Lunar surface) on weightbearing bone remains undefined; a new model (the partial G mouse) provides for graded reductions in weightbearing. It was hypothesized that mice exposed ...
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(Texas A&M University, 2007-09-17)Blood-borne biochemical markers were used to track comparative rates of bone turnover in horses fed differing amounts of Ca, P and Mg. Bone turnover was tracked by serum osteocalcin, bone resorption by the carboxyterminal ...
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(2009-05-15)Mechanical unloading and food restriction (FR) are leading causes of bone loss, which increase the risk of fracture later in life. Leptin, a 16kDa cytokine like hormone principally produced by white adipocytes, may be ...
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(2015-11-17)Spinal contusion injuries are characterized by an increased excitation of the immune system that results in inflammation and heightened expression levels of pro-inflammatory cytokines in the central nervous system (CNS) ...
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(2012-02-14)Extended periods of mechanical unloading are known to be detrimental to bone health. Astronauts who spend months in microgravity aboard the International Space Station (ISS) are at particular risk. It is anticipated that ...
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(Texas A&M University, 2007-09-17)Hindlimb unloading is a widely used model for studying the effects of microgravity on a skeleton. Hindlimb unloading produces a marked loss in bone due to increased osteoclast activity. Electrical muscle stimulation is ...
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(2018-05-06)As the focus shifts to potential Lunar and Mars missions, there are many aspects of the space environment that are still unknown, one of those being radiation exposure. There are many radiation studies examining the effects ...
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(2016-05-09)Adults suffering from lower back pain often find that the cause of pain is degenerative disc disease. While non-surgical treatment is preferred, spinal fusion and total disc replacement remain surgical options for the ...
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(2020-04-27)Chronic inflammation leads to bone loss and fragility. Signaling of proinflammatory cytokines, like tumor necrosis factor-alpha (TNFα), is integral to promote bone resorption. Dietary modulation of pro-inflammatory cytokines ...
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(2017-02-13)The purpose of this study was to investigate the biological changes in bone density and bone modeling of the cortical bone when increasing the amount of cortical damage. Using a split body design, rabbit tibias were ...
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(2020-07-20)Potential for aquatic exercise to affect cartilage and bone metabolism in young horses was investigated. Thirty Quarter Horse yearlings were stratified by age, body weight (BW), and sex and randomly assigned to one of three ...
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(2013-04-19)Astronauts in space flight missions are exposed to increased iron (Fe) stores and galactic cosmic radiation, both of which independently induce oxidative stress. Oxidative stress can result in protein, lipid, and DNA ...
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(2017-05-08)Microgravity-related bone loss in astronauts is a well-known consequence of space travel. These losses are a result of the catabolic reaction of the skeleton to unloading. Anti-catabolics like bisphosphonates (BPs) have ...
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(2019-11-29)Extracellular matrix (ECM) is a primary component of the osteogenic microenvironment, providing support for attachment, proliferation, and differentiation to facilitate bone growth and maintenance. Previously we have shown ...
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(2011-05-06)The purpose of this research project was to determine the overall effects of ibuprofen on bone formation in response to simulated resistance training in adult female rats. Ibuprofen is a common and generally safe non-steroidal ...
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(2019-04-26)Cranio-maxillofacial (CMF) bone defects are most commonly treated with autografts despite their many limitations. Namely, the rigid autografts are difficult to shape and fit into complex defect geometries, resulting in ...
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(2009-05-15)This thesis concentrates on discovering the best consolidant or consolidants for stabilizing a Columbian mammoth’s sub-fossilized mandibles, a distal femur, an ulna, a radius, and a tooth. It was recovered from a wet, sandy ...
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(Texas A&M University, 2004-11-15)Prolonged periods of non-weightbearing activity result in a significant loss of bone mass which increases the risk of fracture with the initiation of mechanical loading. The loss of bone mass is partially driven by declines ...
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(2013-02-04)Partial weightbearing that simulates Lunar gravity (one-sixth of Earth’s gravitational force) results in a loss of bone volume. High-energy radiation like that found in galactic cosmic radiation exposure also negatively ...