Browsing by Subject "Proteomics"
Now showing items 1-9 of 9
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(2019-04-15)Selective reaction monitoring (SRM) has become one of the main methods for low-mass range targeted proteomics by mass spectrometry (MS). However, in most SRM-MS biomarker validation studies the sample size is very small, ...
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(2012-07-16)The small-sample size issue is a prevalent problem in Genomics and Proteomics today. Bootstrap, a resampling method which aims at increasing the efficiency of data usage, is considered to be an effort to overcome the problem ...
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(Texas A&M University, 2005-08-29)Separations coupled to mass spectrometry (MS) are widely used for large-scale protein identification in order to reduce the adverse effects of analyte ion suppression, increase the dynamic range, and as a deconvolution ...
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(2014-04-25)Mass spectrometry (MS) has been established as important analytical tool in the characterization of an array of analyte classes, including biological samples. However, without hyphenation with other techniques, the approach ...
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Noncanonical Amino Acid Incorporated Photocaged Cysteine for Multiple Cysteine Based ACPL Approach (2020-04-30)Today, proteins and protein functionality are a major focus of biological chemistry. Every synthesized protein has a unique and innate biological function, understanding these functions and their application has been at ...
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(2019-02-28)Chronic hepatitis can present a diagnostic challenge, with different types of chronic hepatic disease being associated with similar clinical and laboratory findings. Clinical signs of chronic hepatitis are often non-specific; ...
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(2014-08-13)Research carried out in this dissertation aims to discover and validate novel gene functions in plant defense and growth. Plants deploy many mechanisms to respond and overcome biological, physical, and environmental ...
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(2013-03-27)This dissertation consists of four different topics in the areas of proteomics, genomics, and cardiology. First, a data-based method was developed to assign the subcellular localization of proteins. We applied the method ...
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(2012-07-16)Proteomics serves an important role at the systems-level in understanding of biological functioning. Mass spectrometry proteomics has become the tool of choice for identifying and quantifying the proteome of an organism. ...