Browsing by Subject "Peptides"

Now showing items 1-8 of 8

    • Development and Advancement of Phage Display Techniques for the Identification of Therapeutic Peptides 
      Hampton, Joshua Trae (2023-05-03)
      Peptides represent an emerging class for drug discovery, with the number of therapeutic peptides nearly doubling in the past twenty years. In spite of the development of many different screening techniques to identify ...
    • Isolation and characterization of two peptides specific to soybean nodules 
      Madtes, Paul Clayton (Texas A&M University. Libraries, 1980)
      Two low molecular weight peptides, each with a molecular weight of about 5.000, were isolated from soybean nodules. The levels of these peptides were positively correlated with the level of nitrogenase activity. These ...
    • Kinetic and crystallographic analysis of porcine pancreatic elastase-ligand interactions 
      Takahashi, Lori Hina (Texas A&M University. Libraries, 1987)
      Elastase (EC 3.4.21.11) is normally involved in the degradation of elastin, and is believed to be the primary agent responsible for the induction of several degenerative connective tissue diseases. The primary subsite ...
    • Overproduction and utilization of enzymes in synthetic organic chemistry 
      Barbas, Carlos Francis (Texas A&M University. Libraries, 1989)
      The utility of papain in the synthesis of peptides containing D or unusual amino acids has been demonstrated. A novel one-step synthesis of tripeptides has been developed using papain. The amidase activity of a number of ...
    • Peptide sequencing by mass spectrometry 
      Norman, Eric Jesse (Texas A&M University. Libraries, 1977)
      Dipeptides were concerted to the N-acetyl-O-n-butyl derivatives and individual mass spectra were recorded. A library of more than 50 of these spectra were placed on magnetic tape. Dipeptide derivative mixtures were prepared ...
    • Studies in enzymatic peptide synthesis 
      West, James Blair (Texas A&M University. Libraries, 1988)
      Chapter I. The incorporation of D-amino acids into peptides via kinetic approach enzymatic peptide synthesis is examined. D-amino acid esters were found to be fairly efficient acyl-acceptors under conditions of high organic ...
    • Synthesis and evaluation of the biological activity of analogues of leupeptin 
      McConnell, Rose M. (Texas A&M University. Libraries, 1983)
      Leupeptin, N-acetyl or N-propionyl-L-leucyl-L-leucyl-DL-argininal, is a potent inhibitor of trypsin-like enzymes; however, it is not selective within this proteolytic class. In an effort to increase selectivity among ...
    • Synthesis and evaluation of the biological activity of analogues of pepstatin 
      Liu, Wu-Schyong (Texas A&M University. Libraries, 1980)
      Synthesis of all four stereoisomers of the novel amino acid statine, 4-amino-3-hydroxy-6-methylhepatanoic acid, and alastatine, 4-amino-3-hydroxypentanoic acid has been accomplished. Several tripeptide analogues of pepstatin ...