Browsing by Subject "Nck"
Now showing items 1-4 of 4
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Modulation of Endothelial Cytoskeletal Dynamics and YAP Localization by Angiogenic Factors
(2017-05-05)Angiogenesis, the formation of new blood vessels from pre-existing ones, plays a crucial role in physiological processes and various pathological conditions including cancer. Angiogenic factor stimulation, including ... -
Role of Nck adaptors in the regulation of endothelial cell-cell adhesion
(2011-08-08)The establishment of endothelial cell-cell contacts is critical for the development and maintenance of the vascular network. Endothelial cell adherens junctions (AJ) are cell-cell adhesion complexes consisting of clusters ... -
THE ROLE OF Nck ADAPTORS IN ENDOTHELIAL CELL POLARITY
(2012-05-08)The establishment of a polarized endothelial layer is essential for normal vascular organization. This project examined the role of actin cytoskeleton remodeling by Nck adaptors in the polarized organization of endothelial ... -
The Role of Nck in Breast Carcinoma Cell Invasion and Metastasis
(2015-07-15)The high incidence of invasive breast carcinomas, which accounts for about 90% of all breast cancer-related deaths, underscores the need for new and more effective therapeutic approaches to block the development of the ...