Browsing by Subject "ATCase"
Now showing items 1-6 of 6
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(1982)The research reported in this thesis demonstrates that the initial steps for pyrimidine biosynthesis in the cellular slime mold Dictyostelium discoideum are catalyzed by the enzymes carbamoyl phosphate synthetase (CPSase, ...
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(1977)A key point in the regulation of pyrimidine biosynthesis by prokaryotic organisms is the enzyme Aspartate Transcarbamylase. This enzyme catalyzes the reaction of carbamyl phosphate plus aspartate to yield carbamyl aspartate, ...
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(1983)Aspartate transcarbamylase (ATCase, EC 2.1.3.2) allosterically modulates de novo pyrimidine biosynthesis in the enteric bacteria. This modulation differs in Escherichia coli and Serratia marcescens, with CTP allosterically ...
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(1985)This research project focused on the production of monoclonal antibodies to the holoenzyme aspartate transcarbamoylase (ATCase) and to its component catalytic and regulatory subunits. The hybridoma cell lines were prepared ...
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(1985)The de novo pyrimidine biosynthetic pathway produces the pyrimidine end products uridine-5'-triphosphate (UTP) and cytidine-5’-triphosphate (CTP), which lead to the synthesis of new DNA and RNA for cell growth. Aspartate ...
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(1978)In these studies, Dictyostelium discoideum nucleotide metabolism during cellular development was examined. Aspartate Transcarbamylase (ATCase) is the first enzyme unique to pyrimidine synthesis de novo and it was found to ...