Now showing items 1-20 of 32

    • Antibodies recognizing a highly expressed putative antigen of CA-MRSA and methods of use 

      Hook, Magnus; Labandeira-rey, Maria; Bowden, Gabriela M. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2012-02-28)
      The present invention provides MSCRAMM® proteins from S. aureus which are putative highly-expressed antigens from methicillin-resistant S. aureus, including communit-associated MRSA (CA-MRSA), and these antigens can thus ...
    • Biosensor compositions and methods of use 

      Bayley, Hagan P.; Howorka, Stefan G.; Movileanu, Liviu (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2005-07-12)
      Provided are pore-subunit polypeptides covalently linked to one or more sensing moieties, and uses of these modified polypeptides to detect and/or measure analytes or physical characteristics within a given sample.
    • Collagen binding protein compositions and methods of use 

      Hook, Magnus; Patti, Joseph M.; House-pompeo, Karen; Sthanam, Narayana; Symersky, Jindrich (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2001-09-11)
      Disclosed are the cna gene and cna-derived nucleic acid segments from Staphylococcus aureus, and DNA segments encoding cna from related bacteria. Also disclosed are Col binding protein (CBP) compositions and methods of ...
    • Compositions and methods related to toll-like receptor-3 

      Kao, Cheng C.; Tharachaparamba, Ranjith Kumar (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2011-11-29)
      The invention relates to compositions and methods related to Toll-like receptor (TLR) polypeptides. In some embodiments, the invention relates to managing TLR3 related diseases. In further embodiments, the invention relates ...
    • Cross-reactive displacing antibodies from collagen-binding proteins and method of identification and use 

      Hook, Magnus; Xu, Yi; Speziale, Pietro; Visal, Livia; Casolini, Fabrizia; Patti, Joseph M.; Patel, Pratiksha; Domanski, Paul (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2007-07-10)
      Antibodies to the CNA protein and to other regions from the collagen binding domain, including domain CNA19, are provided, and antibodies produced in this manner have been shown to be cross reactive to both Staphylococcus ...
    • DbpA compositions 

      Guo, Betty P.; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2001-04-10)
      Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
    • Decorin binding protein compositions 

      Guo, Betty; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2001-05-08)
      Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
    • Decorin binding protein compositions and methods of use 

      Guo, Betty P.; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2001-06-19)
      Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
    • Decorin binding protein compositions and methods of use 

      Guo, Betty; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 1998-12-29)
      Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
    • Decorin proteoglycan inhibitor of fibrinogen blood clotting 

      Höök, Magnus; Dugan, Tracey A. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2006-08-22)
      The present invention provides compositions and methods of inhibiting fibrin(ogen) clot formation by utilizing decorin proteoglycan as an anticoagulating and antithrombotic agent. The decorin proteoglycan comprises a decorin ...
    • Designer collagens and use thereof 

      Russell, Brooke H.; Hook, Magnus; Hahn, Mariah S.; Cosgriff-hernandez, Elizabeth M.; Seo, Neungseon; Xu, Marvin Xuejun (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2013-12-31)
      The present invention identified a recombinant synthetic collagen containing a triple helical backbone protein produced in a prokaryotic expression system where the protein contains at least one ‘inserted’ biologically ...
    • Extracellular matrix-binding proteins from Staphylococcus aureus 

      Patti, Joseph M.; Foster, Timothy J.; Josefsson, Elisabet; Eidhin, Deidre Ni; Hook, Magnus A. O.; Perkins, Samuel E. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2008-06-03)
      Isolated extracellular matrix-binding proteins, designated ClfB, SdrC, SdrD and SdrE, and their corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or ...
    • Feline CD86 polypeptides and nucleic acids 

      Cochran, Mark D.; Collisson, Ellen W.; Choi, In-soo; Winslow, Barbara J.; Cochran, Mark D. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2011-12-06)
      The present invention provides isolated and purified DNA encoding feline CD80 (B7-1) ligand, feline CD86 (B7-2) ligand, feline CD28 receptor, or feline CTLA-4 (CD152) receptor, as well as vectors comprising nucleic acid ...
    • FGF-affinity chromatography 

      Mckeehan, Wallace L.; Luo, Yongde (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2004-11-02)
      The present invention relates to a method and apparatus for isolating anticoagulant heparin or heparan sulfate by binding the anticoagulant heparin or anticoagulant heparan sulfate onto an affinity matrix and separating ...
    • HSP20 inhibits amyloidogenesis and neurotoxicity 

      Ficht, Allison; Good, Theresa; Carson, Ken; Lee, Sundmun (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2014-04-29)
      The present invention compositions and methods of using at least a portions of an isolated and purified α-crystallin polypeptide that includes one or more β-pleated sheets and that prevents neurotoxicity and amyloidogenesis.
    • MHC II analog from Staphylococcus aureus 

      Hook, Magnus; Jonsson, Klas; Patti, Joseph M.; Gurusiddappa, Sivashankarappa (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 1997-07-15)
      Staphylococcus aureus can bind a number of different extracellular matrix proteins. Recent studies have shown that one particular Staphylococcus protein has the capacity of binding several different matrix proteins. The ...
    • Multicomponent vaccines 

      Patti, Joseph M.; Foster, Timothy J.; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2004-03-09)
      Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies ...
    • Nucleic acid encoding feline CD86 

      Collisson, Ellen W.; Choi, Insoo; Winslow, Barbara J.; Cochran, Mark D. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2006-07-18)
      The present invention provides isolated and purified DNA encoding feline CD80 (B7-1) ligand, feline CD86 (B7-2) ligand, feline CD28 receptor, or feline CTLA-4 (CD152) receptor, as well as vectors comprising nucleic acid ...
    • Nucleotide and amino acid sequences of asporins 

      Henry, Stephen P.; Hook, Magnus A. O.; Mayne, Richard (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2007-12-04)
      Mouse asporin protein and nucleic acid sequences are disclosed. The protein contains a unique aspartic acid region near the N-terminus. The central domain contains ten leucine rich repeats. Sequences consistent with other ...
    • Oral immunization with transgenic plants 

      Arntzen, Charles J.; Mason, Hugh S.; Haq, Tariq A. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2001-02-27)
      The oral vaccines and oral vaccine adjuvants of the present invention are produced in transgenic plants and then administered through the consumption of the transgenic plant. DNA sequences both natural and synthetic encoding ...