Browsing by Author "Darensbourg, Marcetta Y"
Now showing items 1-20 of 38
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Nguyen, Hao AnhNatural metalloenzymes not only display extraordinary catalytic activities in biological systems, but also are models for chemists to design organometallic catalysts. Bioinorganic chemical researchers in this field focus ...
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Brawley, Hayley N (2021-06-01)Low-molecular-mass (LMM) transition metal complexes are thought to play essential roles in metal ion trafficking, regulation, and signaling in biological systems. Their chemical identities remain largely unknown due to ...
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David Lopez, Amanda (2015-10-07)The work contained in this dissertation focuses on the synthesis and characterization of dirhodium (II,II) compounds and studies of their anticancer activities against cervical and ovarian cancer cell lines. It has been ...
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Bethel, Ryan D (2014-08-20)The discovery of a diiron organometallic active site, found in the [FeFe]-Hydrogenase (H2ase) enzyme, has led to a revisiting of the classic organometallic chemistry involving the Fe-Fe bond and bridging ligands. This ...
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Lunsford, Allen Michael (2016-12-08)The discovery of cyano-iron carbonyls in the hydrogenases has inspired synthetic efforts to reproduce the active sites of these efficient H2-producing or H2-oxidation enzymes. Recent demonstration of the possibility of ...
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Timpa, Samuel D (2014-07-29)Transition metal catalyzed cross-coupling reactions of aryl halides have revolutionized the synthesis of organic molecules. These reactions, which are commonly catalyzed by group 10 metals, have found applications including ...
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Leamer, Lauren Anne (2013-05-06)The fluoride anion plays an important role in dental health and as a result is added to drinking water at low concentrations. If the concentration of fluoride is too high however, skeletal fluorosis can occur. Because of ...
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Wititsuwannakul, Taveechai (2022-07-20)Counter ion effects on the rates of catalytic reactions and enantioselectivities originated from hydrogen bond donor catalysts are computationally established. First, cat-ion/anion interactions are studied in salts of ...
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Ding, Shengda (2017-12-08)Hydrogenases are enzymes capable of catalyzing, reversibly, coupling of protons and electrons into dihydrogen. The active sites of both [NiFe]- and [FeFe]-hydrogenases feature a M₂S₂ core, where two first-row transition ...
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Yeung, Andrew D (2014-09-25)The use of carbon dioxide as a chemical feedstock for the copolymerization with epoxides to give polycarbonates, and for coupling with hydrocarbons to give carboxylic acids, was probed using computational chemistry. ...
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Das, Anuvab (2020-11-17)Metal–ligand (M–L) multiply bonded complexes hold a central place in inorganic chemistry and catalysis: From fundamental and historical perspectives, these species have played a critical role in the articulation of important ...
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Fan, Jingwei (2016-05-18)Recent decades have witnessed extensive utilization of polypeptide materials in nanomedical applications, such as serving as scaffolds for tissue engineering, matrices for drug and gene delivery, and responsive materials ...
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Rampersad, Marilyn Vena (Texas A&M University, 2007-04-25)Electronic and steric parameters for square planar NiN2S2 complexes as bidentate, S-donor ligands have been established. According to the (CO) stretching frequencies and associated computed Cotton-Kraihanzel force constants ...
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Lim, Young (2015-07-16)The development of well-defined polymeric nanoparticles (NPs) as delivery carriers for antimicrobials targeting human infectious diseases requires rational design of the polymer template, an efficient synthetic approach ...
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Jung, Hunmin (2014-12-17)The goal of this study was to develop drugs that exclusively affect pathogenic dihydrofolate reductase (DHFR) without causing harm to the human counterpart. To achieve that goal, a well-known dihydrofolate reductase (DHFR) ...
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Gulten, Gulcin (2014-03-18)Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis (TB), which is one of the leading infectious diseases worldwide. The current therapy for drug-sensitive TB is complex and lasts for at least six months. ...
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Coll, Ryan Patrick (2021-08-04)Dirhodium complexes are used for a broad scope of applications due, in part, to the presence of a stable RhII-RhII bond which has a remarkable ability to adapt to a rich variety of ligands for the tuning of electronic and ...
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Pectol, Dale Chase (2021-08-25)The therapeutic nature and mechanisms of in vitro nitric oxide (NO) release from dinitrosyl iron complexes (DNICs) are explored herein. First, the ideal primary coordination environment for the sustained liberation of NO ...
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Tong, YichengLiterature Review Clean energies, as solar and wind power, have been used to produce electric energy, but the storage of electric power in batteries is not sufficient, and the production of batteries also generates waste. ...
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Choi, Hyeran (2016-07-28)Iron-sulfur (Fe-S) clusters are cofactors that are required for many biological processes. Conserved biosynthetic pathways synthesize Fe-S clusters and deliver clusters to target proteins using an elaborate distribution ...