Browsing by Author "Chapkin, Robert S."
Now showing items 1-20 of 31
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Turk, Harmony F.; Barhoumi, Rola; Chapkin, Robert S.; Holowka, David (PloS One, 2012)
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Monk, Jennifer M.; Turk, Harmony F.; Fan, Yang-Yi; Callaway, Evelyn; Weeks, Brad; Yang, Peiying; McMurray, David N.; Chapkin, Robert S. (Mediators of Inflammation, 2014)
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Cho, Young Mi (2012-10-19)Accumulated genetic and epigenetic abnormalities contribute to the development of colon cancer. We have shown that a combination of fish oil (containing decosahexaenoic acid, DHA, 22:6 n-3) and pectin (fermented to butyrate ...
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Leonardi, Tety (Texas A&M University, 2006-08-16)Colon cancer is the third most common cancer in the United States. However, evidence indicates that a proper diet abundant in fruits and vegetables may be protective against colon cancer development. Bioactive compounds ...
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Covert, Kristy Lynn (Texas A&M University, 2006-08-16)We have previously shown that dietary fish oil and fiber, particularly the highly-fermentable pectin, are protective against colon cancer in a rat model of carcinogenesis. Therefore, based upon the current body of literature ...
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Monk, Jennifer M.; Hou, Tim Y.; Turk, Harmony F.; Weeks, Brad; Wu, Chaodong; McMurray, David N.; Chapkin, Robert S.; Bassaganya-Riera, Josep (PloS One, 2012)
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Cortes Acosta, Sergio David (2015-10-02)The Ras-EGFR-MAPK signaling axis is chronically up-regulated in colon cancer, and pharmacological inhibition of signaling through Ras and/or EGFR has been shown to prevent colon tumor formation. Recent evidence suggests ...
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Seo, Jeongmin (Texas A&M University, 2006-04-12)Correct localization of lipidated cytosolic proteins to the plasma membrane (PM) is mediated by interactions between lipid anchors of proteins and cell membranes. Previously, dietary fish oil and its major n-3 polyunsaturated ...
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Han, Huajun (2020-07-27)The aryl hydrocarbon receptor (AhR) is a ligand-activated basic helix-loop-helix transcription factor that binds and senses cues from promiscuous ligands including environmental toxicants and dietary/microbiota-derived ...
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The effect of dietary n-3 polyunsaturated fatty acids on T cell subset activation-induced cell death Switzer, Kirsten Collette (Texas A&M University, 2004-11-15)Dietary n-3 polyunsaturated fatty acids (PUFA) have been shown to potently attenuate T cell-mediated inflammation, in part, by suppressing T cell activation and proliferation. Apoptosis is an important mechanism for ...
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Mann, John Clifford (Texas A&M University, 2006-10-30)The ability of ionizing radiation to enhance colon carcinogenesis and the role of diet in this process has not been documented. We hypothesized that radiation would enhance the formation of aberrant crypt foci, ACF, known ...
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Sanders, Lisa Merle (Texas A&M University, 2006-08-16)Colon cancer is one of the most commonly diagnosed cancers in the US, yet small intestine cancer is a rare event. While there are many similarities between these two tissues, inherent differences such as redox status, may ...
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Barhoumi, Rola; Mouneimne, Youssef; Chapkin, Robert S.; Burghardt, Robert C.; Schunck, Wolf-Hagen (PloS One, 2014)
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Newton, Anne Henry (Texas A&M University, 2005-11-01)We have previously shown that dietary fish oil and the fiber pectin protect against colon cancer in rats by increasing apoptosis induced by reactive oxygen species (ROS) at the initiation stage of tumorigenesis. We ...
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Weige, Charles (2012-10-19)Hormone replacement therapy and estrogen replacement therapy have shown the ability to reduce risk of colon cancer development in clinical and animal studies, but in vitro research has been unable to reproduce an estradiol ...
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Neerman, Michael Frederick (Texas A&M University, 2005-08-29)Often associated with chemotherapy are the dangerous and sometimes lifethreatening side effects towards non-cancerous tissue that can occur while on such drug regimens. The design and utilization of macromolecular drug ...
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Ly, Lan H. (Texas A&M University, 2005-02-17)Consumption of fish oils (FO) enriched with the n-3 polyunsaturated fatty acids (PUFA), docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), is beneficial to a variety of inflammatory disorders due, in part, to the ...
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Bonilla, Diana L.; Ly, Lan H.; Fan, Yang-Yi; Chapkin, Robert S.; McMurray, David N.; Doherty, T. Mark (PloS One, 2010)
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Ahn, Ji-Eun; Zhou, Xin; Dowd, Scot E.; Chapkin, Robert S.; Zhu-Salzman, Keyan; Palli, Subba Reddy (PloS One, 2013)
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Petrescu, Anca Daniela (Texas A&M University, 2004-09-30)Cholesterol and fatty acyl-coenzymeA thioesters are signalling molecules with role in regulation of genes involved in lipid and glucose transport and metabolism. The studies described herein focused on three proteins that ...