Browsing by Author "Chapkin, Robert"
Now showing items 1-15 of 15
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Su, Junjie (2012-02-14)Finding reliable gene markers for accurate disease classification is very challenging due to a number of reasons, including the small sample size of typical clinical data, high noise in gene expression measurements, and ...
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Koonchanok, Ratanond (2017-12-04)Sparse canonical correlation analysis (sparse CCA) is a method for identifying sparse linear combinations of the two sets of variables that are highly correlated with each other, given that those two sets of measurements ...
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Zheng, Yuanning (2021-07-15)Breast cancer is the most commonly diagnosed non-cutaneous cancer among women in the United States. Inheritable genetic factors, such as BRCA gene mutations, account for only 5-10% of the risk for developing breast cancer. ...
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Mantilla Rojas, Carolina (2019-11-13)Colorectal cancer (CRC) ranks among the third most common human malignant diseases and is one of the leading causes of cancer-related deaths globally. The epidermal growth factor receptor (EGFR) is recognized as an important ...
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Navarro, Sandi; Neuhouser, Marian; Ting-Yuan David Cheng; Tinker, Lesley; Shikany, James; Snetselaar, Linda; Martinez, Jessica; Kato, Ikuko; Beresford, Shirley; Chapkin, Robert; Lampe, Johanna (Nutrients, 2016)
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Halim, Vera (2012-02-14)Studies had shown that leucine supplementation increases insulin sensitivity and it has been studied that n-3 PUFA may have an anti-inflammatory effect in adipocytes. However, the extent to which dietary sources such as ...
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White, Michael (2015-06-03)Fibrosis is a disease in which scar tissue invades healthy organs and reduces their function. Fibrosis is involved in 45% of deaths in the United States, yet little is known about the signaling that underlies the early ...
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Tsai, Pai Chi (2014-05-05)Maternal alcohol consumption during pregnancy, especially during the first and second trimester, can cause the wide range of severe birth defects classified as fetal alcohol spectrum disorder (FASD). FASD is a wide spectrum ...
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George, Nysia I. (2010-01-16)Microarray technology has become a dynamic tool in gene expression analysis because it allows for the simultaneous measurement of thousands of gene expressions. Uniqueness in experimental units and microarray data platforms, ...
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Shrestha, Rupesh (2021-12-09)Nuclear receptor 4A1 (NR4A1) is an orphan receptor that is overexpressed in several cancers and is known for its pro-oncogenic activities in solid tumors. NR4A1 plays a crucial role in multiple cancers and regulates ...
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Tripathi, Utkarsh (2017-12-13)We have previously shown that partial inhibition of mitochondrial complex I activity with a small molecule tricycle pyrone compound (code name CP2) averted the development of cognitive and behavior phenotypes in multiple ...
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Kim, Eunjoo; Davidson, Laurie; Zoh, Roger; Hensel, Martha; Salinas, Michael; Patil, Bhimanagouda; Jayaprakasha, Guddadarangavvanahally; Callaway, Evelyn; Allred, Clinton; Turner, Nancy; Weeks, Brad; Chapkin, Robert (Cell Death & Disease, 2016)
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Saldua, Meagan Alyssa (2012-02-14)Many Americans are afflicted with inflammation of the colon. They are also at a higher risk of developing colon cancer. Confocal microscopy of bulk epithelial tissue has the potential to provide information on tissue ...
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Ying, Wei (2015-02-02)The recruitment of immune cells into adipose tissue is a hallmark of obesity and a key event contributing to the development of adipose tissue inflammation and insulin resistance. However, the mechanisms regulating functions ...
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Pan, Quan (2020-11-20)Liver and adipose tissue are crucial for blood glucose and energy homeostasis, while unsuppressed hepatic glucose production (HGP) causes hyperglycemia and imbalanced energy expenditure could lead to excessive fat storage ...