Browsing by Author "Chang, Jiang"
Now showing items 1-20 of 20
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Ji, Pengfei (2022-01-03)Sepsis is a threat to human healthy and caused by infection with a systemic inflammatory response. Sepsis ranges from endotoxemia to more severe and long-term effects. Moreover, the low blood pressure and inflammation ...
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Wei, Lei; Surma, Michelle; Gough, Gina; Shi, Stephanie; Lambert-Cheatham, Nathan; Chang, Jiang; Shi, Jianjian; Kanthou, Chryso (PloS One, 2015)
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Kim, Eun Young; Chen, Li; Ma, Yanlin; Yu, Wei; Chang, Jiang; Moskowitz, Ivan P.; Wang, Jun; Milstone, David S. (PloS One, 2011)
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Liu, Junchen (2017-12-07)Acquisition of ectopic expression of type 1 receptor for the fibroblast growth factor receptor type1 (FGFR1) in prostate cancer (PCa) is well documented. However, while it is known that FGFR confers a growth advantage and ...
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Tong, Yanzheng (2014-04-10)The NOD-like receptor protein NLRC5 inhibits TLR-induced NF-ҡB and viral infection-mediated type I interferon signaling in vitro. In the first project, we generated NLRC5 knockout mice to characterize the regulatory function ...
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Li, Yinyin (2014-08-06)The innate immune system is considered as the first line of host defense during infection to recognize the pathogen-associated molecular patterns (PAMPs) by several classes of germline-encoded pattern-recognition receptors ...
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Zhang, Min (2015-06-16)Use of high-throughput sequencing technology has revolutionized our ability to study heart development and regeneration. However, extracting crucial information from large-scale datasets is challenging. Here we demonstrated ...
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Zhang, Xiaowei; Wang, Xiaohong; Zhu, Hongyan; Kranias, Evangelia G.; Tang, Yaoliang; Peng, Tianqing; Chang, Jiang; Fan, Guo-Chang; Qin, Gangjian (PloS One, 2012)
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An Intragenic SRF-Dependent Regulatory Motif Directs Cardiac-Specific microRNA-1-1/133a-2 Expression Li, Qi; Guo, Junli; Lin, Xi; Yang, Xiangsheng; Ma, Yanlin; Fan, Guo-Chang; Chang, Jiang; Yan, Wei (PloS One, 2013)
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Yang, Tingli (2017-12-14)High-fat diet (HFD)-induced obesity is a risk factor contributing to cardiovascular disease. Excessive accumulation of fatty acids in the heart can cause cardiac dysfunction and heart failure and is referred to as lipotoxic ...
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Yue, Xiaojing (2015-04-28)In human end-stage heart failure patients, the activation of Rho kinase 1 (ROCK1) is observed in the heart. ROCK1 activation promotes the activation of caspase 3, which results in a feed-forward loop contributing to myocyte ...
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Weng, Kuo-Chan (2014-04-16)Heart disease remains the leading cause of death worldwide. By understanding the regulating networks during cardiac development we can exploit those networks to manipulate adult cells into cardiac progenitors and provide ...
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Cao, Jin (2014-04-17)Gluconeogenesis is a biochemical process through which the organs or cells can synthesize glucose from non-carbohydrate carbon substrates and is important for blood glucose homeostasis. Multiple enzymes participate in this ...
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Dai, Yuan (2018-02-20)Cardiac inflammatory response after myocardial infarction (MI) is essential to clear necrotic myocardium for cardiac healing, while excessive and prolonged inflammation extends the infarction and promotes adverse cardiac ...
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Andrade, Kelsey Colleen (2018-05-09)Small GTPase Rnd3 participates in a broad spectrum of pathological processes. The downregulation of Rnd3 is observed in heart failure patients, and causes cardiac dysfunction in animal models. The dysfunction of mitochondria ...
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Zhang, Li; Valdez, Joseph M.; Zhang, Boyu; Wei, Lei; Chang, Jiang; Xin, Li; Oshima, Robert (PloS One, 2011)
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ROCK1 Deficiency Enhances Protective Effects of Antioxidants against Apoptosis and Cell Detachment Surma, Michelle; Handy, Caitlin; Chang, Jiang; Kapur, Reuben; Wei, Lei; Shi, Jianjian; Hotchin, Neil A. (PloS One, 2014)
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Zhou, Cissy Chenyi; Chang, Jiang; Mi, Tiejuan; Abbasi, Shahrzad; Gu, Dongmin; Huang, Le; Zhang, WenZheng; Kellems, Rodney E.; Schwartz, Robert J.; Xia, Yang; Milstone, David S. (PloS One, 2012)
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Fu, Chuntang (2019-03-28)Jmjd3, a histone H3K27 demethylase, regulates macrophage and T-cell differentiation, but its role in T-cell trafficking and persistence remains largely unknown. In this dissertation, I show that Jmjd3 deficiency in CD4^+ ...
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Lawless, Lauren Amanda (2022-10-25)Cadmium (Cd) is a natural heavy metal and environmental contaminant, concentrated by industrial activity. Overconsumption or inhalation of this element has been found to induce genotoxicity, ROS production, and apoptosis, ...