Specific binding sites in collagen for integrins and use thereof

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dc.contributor.assigneeThe Texas A&M University System
dc.creatorHook, Magnus
dc.creatorXu, Xuejun
dc.creatorKim, Jiyeun
dc.date.accessioned2019-09-11T17:15:45Z
dc.date.available2019-09-11T17:15:45Z
dc.date.filed2013-02-19
dc.date.issued2019-07-23
dc.description.abstractThe present invention identified a high affinity binding sequence in collagen type III for the collagen-binding integrin I domains. Provided herein are the methods used to characterize the sequence, the peptides comprising this novel sequence and the use of the peptides in enabling cell adhesion. Also provided herein are methods to identify specific integrin inhibitors, sequences of these inhibitors and their use in inhibiting pathophysiological conditions that may arise due to integrin-collagen interaction.en
dc.description.countryUS
dc.format.digitalOriginreformatted digitalen
dc.identifier.patentapplicationnumber13/770852
dc.identifier.urihttps://hdl.handle.net/1969.1/177879
dc.languageEN
dc.publisherUnited States. Patent and Trademark Office
dc.publisher.digitalTexas A&M University. Libraries
dc.rightsPublic Domain (No copyright - United States)en
dc.rights.urihttp://rightsstatements.org/vocab/NoC-US/1.0/
dc.subject.cpcprimaryC07K 14/00
dc.subject.cpcprimaryC07K 7/06
dc.subject.cpcprimaryC07K 14/78
dc.subject.cpcprimaryG01N 33/566
dc.subject.cpcprimaryG01N 33/6887
dc.subject.cpcprimaryG01N 2333/70546
dc.subject.cpcprimaryG01N 2333/78
dc.subject.cpcprimaryG01N 2500/02
dc.subject.cpcprimaryA61P 35/00
dc.subject.cpcprimaryA61P 29/00
dc.subject.cpcprimaryA61P 35/04
dc.titleSpecific binding sites in collagen for integrins and use thereofen
dc.typeUtility patenten

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