Data sets for Biomolecular interactions studied by low-field NMR using SABRE hyperpolarization
No Thumbnail Available
Date
2023-09-07
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
This entry contains data sets for Pham, P and Hilty, C. Biomolecular interactions studied by low-field NMR using SABRE hyperpolarization, Chem. Sci., 2023, DOI: 10.1039/D3SC02365F
Description
The high_concentration.csv contains the data for plotting Figures 2f and S11, which correspond to the conditions of free ligand (655 ± 31 μM reporter), non-competition (ligand and 11.7 ± 0.5 μM of protein), and competition (ligand, protein, and 142 ± 4 μM of competitor).
The medium_concentration.csv contains the data for plotting Figures 3 and S13, which correspond to the conditions of free ligand (131 ± 6 μM reporter only), non-competition (reporter and 5.7 ± 0.3 μM protein), and competition (reporter, protein, and 42.5 ± 3.8 μM competitor).
The low_concentration.csv contaoins the data for plotting Figure S15, which corresponds to the conditions of free ligand (65.5 ± 3.1
μM reporter), non-competition (reporter and 5.7 ± 0.3 μM protein), and competition (reporter, protein, and 28.6 ± 2.5 μM competitor).
Keywords
NMR Spectroscopy, low-field NMR, parahydrogen, protein-ligand interactions