Activity Of Transfer RNA Methyltransferases During Insect Metamorphosis

Loading...
Thumbnail Image

Date

1977

Journal Title

Journal ISSN

Volume Title

Publisher

Abstract

Transfer RNA (tRNA) methyltransferases were partially purified from Manduca sexta prepupa larvae and 2-day-old pupae. The purification procedure involved pH 5 precipitation, gel filtration to remove endogenous inhibitors and activators, and ammonium sulfate precipitation. To ensure maximal activation of all preparations, 0.36 M ammonium acetate was used in the reaction mixture. Escherichia coli B tRNA was the methyl accepting substrate, and ¹⁴CH₃-S-adenosylmethionine was the methyl donor. The prepupa larvae had a specific activity of 140 units/mg protein. The 2-day-old pupae had a specific activity of 430 units/mg protein.

Description

Program year: 1976/1977
Digitized from print original stored in HDR

Keywords

Transfer RNA, Manduca sexta, prepupa larvae, pupae

Citation