Browsing Undergraduate Research Scholars Capstone (2006–present) by Department "Biochemistry/Biophysics"
Now showing items 1-20 of 22
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(2013-12-16)Obtaining structural information on the extracellular domain (ECD) of α3 subunits of nicotinic acetylcholine receptors (nAChRs) by x-ray crystallography is desirable for the design of drugs intended to therapeutically ...
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(2014-12-16)Acinetobacter baumannii is a Gram-negative nosocomial pathogen that has been difficult to eradicate from hospital settings due to its ability to form biofilm and colonize biotic and abiotic surfaces. Phages may represent ...
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(2013-02-04)RHD3, an integral membrane protein with active GTPase activity found in plants, has been recently highlighted as an ER remodeling protein. While the function of this protein is unknown, it is proposed that RHD3 acts in the ...
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(2013-12-05)Although significant research is currently being conducted to study human cancers, the use of in vivo models is time consuming and costly. Recent findings have documented the use of mouse intestinal crypt organoids as a ...
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(2013-02-04)In addition to their primary biological function, many proteins are at least moderately capable of catalyzing secondary, promiscuous activities that may have a major role in enzyme evolution. Mounting evidence supports the ...
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(2013-09-26)The lambda lysis genes Rz and Rz1 play an important role at the final step of bacterial cell lysis. Rz encodes an integral inner membrane protein and Rz1 encodes an outer membrane lipoprotein. These two proteins form a ...
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(2013-09-25)The plant innate immune system is built on a great number of processes, many of which are uncharacterized, or incompletely identified. Infection of Arabidopsis thaliana with bac- terium Pseudomonas syringae pv. tomato ...
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(2014-04-08)Mitochondria house the mitochondrial respiratory chain (MRC), the main site for cellular respiration and energy production. The MRC consists of five large protein complexes (I-V) in the inner mitochondrial membrane. Despite ...
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(2014-01-21)Mitochondria house the mitochondrial respiratory chain (MRC), the main site for cellular respiration and energy production. The MRC consists of five large protein complexes (I-V) in the inner mitochondrial membrane. Despite ...
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(2014-04-08)Mitochondria house the mitochondrial respiratory chain (MRC), the main site for cellular respiration and energy production. The MRC consists of five large protein complexes (I-V) in the inner mitochondrial membrane. Despite ...
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(2014-09-22)Burkholderia cenocepacia is one of seventeen opportunistic pathogens that form the Burkholderia cepacia complex (Bcc). In the clinical environment, Bcc species are especially problematic due to their resistance to many ...
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(2013-02-04)Our research investigated a possible target for cardiovascular disease treatment via the G-protein coupled estrogen receptor (GPER). Estrogen mitigates vascular smooth muscle cell (VSMC) proliferation and migration, which ...
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(2013-02-12)Human food-borne pathogen Salmonella enterica ser. Typhimurium has evolved a sophisticated way to avoid the host immune response. Salmonella Typhimurium possesses various virulence factors to ensure successful colonization ...
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(2014-09-18)The impact of hyperinsulinemia on adipose tissue inflammation has been studied for decades in order to try and obtain a better understanding of the underlying effects of cardiovascular diseases and diabetes mellitus. Despite ...
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(2013-09-25)Members of the genus Streptomyces are filamentous and spore forming bacteria that live in soil and aqueous environments. Within these environments, Streptomyces as well as other bacteria play a large role in their environment ...
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(2013-02-04)Pervasive tumors appear to evade immune detection through manipulation of the immune response, though precisely how this occurs is not well understood. A further understanding of these details may be achieved through the ...
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(2013-02-04)Galectins represent a group of proteins that bind β-galactosyl-containing glycoconjugates and share primary structural homology in their carbohydrate recognition domains. In mammals, galectins contribute to cell-cell ...
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(2013-02-04)Stroke is the fourth leading cause of death worldwide. Low levels of IGF-1, a known neuroprotectant, correspond to aging and increased severity of stroke. We have previously demonstrated that there is an inverse relationship ...
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(2014-08-22)When operating aberrantly, enzymes contribute to the mechanisms of many different diseases, and as such, have proven to be promising targets for the discovery of new drugs. Proteases catalyze the hydrolysis of peptide bonds ...
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(2013-03-22)Galectins are major sugar binding proteins that can be blocked from interactions with its sugar epitopes, galactose, by sialylation. Previous research from Panin lab has showed that sialylation affects the neural excitability. ...