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Now showing items 21-30 of 31
Multicomponent vaccines
(United States. Patent and Trademark Office, 2011-09-13)
Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies ...
Polypeptides and polynucleotides from coagulase-negative staphylococci
(United States. Patent and Trademark Office, 2010-05-04)
Methods for treating or preventing infections from coagulase-negative staphylococci using proteins and polypeptides from coagulase-negative staphylococcal bacteria such as S. epidermidis, including proteins designated SdrF, ...
Method of treating endothelial dysfunction comprising administration of a thrombin peptide derivative
(United States. Patent and Trademark Office, 2012-12-18)
Endothelial dysfunction (ED) is associated with a number of diseases and disorders. Agonists of the non-proteolytically activated thrombin receptor can be used in methods to treat ED or ED-related diseases and disorders.
Decorin binding protein compositions and methods of use
(United States. Patent and Trademark Office, 2001-06-19)
Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
DbpA compositions and methods of use
(United States. Patent and Trademark Office, 2001-11-06)
Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
Monoclonal antibodies recognizing a coagulase-negative staphylococcal protein
(United States. Patent and Trademark Office, 2013-07-02)
Monoclonal antibodies which can bind to the SdrF protein of Staphylococcus epidermidis are provided which can be useful in the treatment and protection against infection from staphylococcal bacteria such as Staphylococcus ...
Inhibitors of mycobacterium tuberculosis malate synthase, methods of making and uses thereof
(United States. Patent and Trademark Office, 2014-03-04)
The present invention provides aryl- or heteroaryl-diketo acid compounds effective to inhibit an activity of a Mycobacterial malate synthase enzyme or to inhibit a malate synthase activity in other bacteria having the ...
Decorin binding protein compositions and methods of use
(United States. Patent and Trademark Office, 1998-12-29)
Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
Variants of the lantibiotic MU1140 and other lantibiotics with improved pharmacological properties and structural features
(United States. Patent and Trademark Office, 2018-05-08)
The invention provides improvements of lantibiotics useful for reducing the numbers of microbes or the reproduction of microbes in or on subjects or objects. One embodiment of the invention provides variants of antibiotics ...
Yeast vaccine vector including immunostimulatory and antigenic polypeptides and methods of using the same
(United States. Patent and Trademark Office, 2020-06-16)
Vaccine compositions including a yeast comprising an immunostimulatory polypeptide and optionally an antigenic polypeptide are provided herein. The immunostimulatory polypeptide and the antigenic polypeptide are expressed ...