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Endocrine therapy for breast cancer: combined treatment with tamoxifen plus alkyl PCDFs
(United States. Patent and Trademark Office, 2000-10-24)
Methods and pharmaceutical combinations for inhibiting estrogen-dependent tumors via the co-administration of antiestrogen triphenylethylenes, including tamoxifen, and alkyl PCDFs.
Compounds and methods for the treatment of cancer
(United States. Patent and Trademark Office, 2008-07-29)
The present invention provides organic arsenicals. Many of these compounds have potent in vitro cytotoxic activity against numerous human tumor cell lines, both of solid and hematological origin, as well as against malignant ...
Specific binding sites in collagen for integrins and use thereof
(United States. Patent and Trademark Office, 2009-04-07)
The present invention identified a high affinity binding sequence in collagen type III for the collagen-binding integrin I domains. Provided herein are the methods used to characterize the sequence, the peptides comprising ...
S-dimethylarsino-thiosuccinic acid s-dimethylarsino-2-thiobenzoic acid s-(dimethylarsino) glutathione as treatments for cancer
(United States. Patent and Trademark Office, 2005-06-28)
Arsenic trioxide, an inorganic compound, is commercially available anti-cancer agent but it carries significant toxicity. Organic arsenicals, on the other hand, are much less toxic, to the extent that the methylation of ...
Potent, simplified derivatives of pateamine A
(United States. Patent and Trademark Office, 2007-06-12)
The present invention provides a compound of Formula I, all of its related stereoisomers, and their pharmaceutically acceptable salts, wherein A—B, K, Q, X, Y, Z, R and R1 are as defined in Claim 1. The present invention ...
Compositions containing C-substituted diindolylmethane compounds
(United States. Patent and Trademark Office, 2007-06-19)
Disclosed are methods and compositions for the treatment of a wide array of cancers and tumors. In illustrative embodiments, diindolylmethanes, C-substituted diindolylmethanes, and analogs thereof have been described, which ...
Recombinant virus expressing foreign DNA encoding feline CD86 and uses thereof
(United States. Patent and Trademark Office, 2007-10-09)
The present invention involves a recombinant virus which comprises at least one foreign nucleic acid inserted within a non-essential region of the viral genome of a virus, wherein each such foreign nucleic acid encodes a ...
S-dimethylarsino-thiosuccinic acid S-dimethylarsino-2-thiobenzoic acid S-(dimethylarsino) glutathione as treatments for cancer
(United States. Patent and Trademark Office, 2009-11-17)
Arsenic trioxide, an inorganic compound, is commercially available anti-cancer agent but it carries significant toxicity. Organic arsenicals, on the other hand, are much less toxic, to the extent that the methylation of ...
S-dimethylarsino-thiosuccinic acid s-dimethylarsino-2-thiobenzoic acid s-(dimethylarsino) glutathione as treatments for cancer
(United States. Patent and Trademark Office, 2006-02-07)
Arsenic trioxide, an inorganic compound, is commercially available anti-cancer agent but it carries significant toxicity. Organic arsenicals, on the other hand, are much less toxic, to the extent that the methylation of ...