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Beta-lactone compounds
(United States. Patent and Trademark Office, 2012-09-04)
The present invention provides compounds having the general structure A, or a pharmaceutically acceptable derivatives thereof:
wherein R is an alkyl group, and R1 comprises at least one moiety selected from a group ...
Compounds and methods for the treatment of cancer
(United States. Patent and Trademark Office, 2012-07-17)
The present invention provides organic arsenicals which may be used to treat numerous human tumor cell lines, both of solid and hematological origin, as well as against malignant blood cells from patients with leukemia.
Belactosin derivatives as therapeutic agents/biological probes and their synthesis
(United States. Patent and Trademark Office, 2012-02-21)
Derivatives of belactosin and their synthesis are disclosed. In certain embodiments, compounds of the present invention exhibit anti-cancer, antiviral, antibiotic, and/or auto-immune therapeutic abilities. In general, ...
C-substituted diindolylmethane compositions and methods for the treatment of multiple cancers
(United States. Patent and Trademark Office, 2012-04-03)
The present embodiment of the invention is generally directed to compositions comprising suspensions of poorly water soluble compounds recrystallized in nanoparticulate sizes ranging from 0.1 to 5 ?m. In addition, the ...
Specific binding sites in collagen for integrins and use thereof
(United States. Patent and Trademark Office, 2012-08-28)
The present invention identified a high affinity binding sequence in collagen type III for the collagen-binding integrin I domains. Provided herein are the methods used to characterize the sequence, the peptides comprising ...