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Extracellular matrix-binding proteins from Staphylococcus aureus
(United States. Patent and Trademark Office, 2008-06-03)
Isolated extracellular matrix-binding proteins, designated ClfB, SdrC, SdrD and SdrE, and their corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or ...
Collagen binding protein compositions and methods of use
(United States. Patent and Trademark Office, 2001-09-11)
Disclosed are the cna gene and cna-derived nucleic acid segments from Staphylococcus aureus, and DNA segments encoding cna from related bacteria. Also disclosed are Col binding protein (CBP) compositions and methods of ...
Cross-reactive displacing antibodies from collagen-binding proteins and method of identification and use
(United States. Patent and Trademark Office, 2007-07-10)
Antibodies to the CNA protein and to other regions from the collagen binding domain, including domain CNA19, are provided, and antibodies produced in this manner have been shown to be cross reactive to both Staphylococcus ...
Multicomponent vaccines
(United States. Patent and Trademark Office, 2004-03-09)
Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies ...