Controlled release vaccines and methods of treating Brucella diseases and disorders
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Methods and compositions for the treatment of Brucella induced diseases and disorders are disclosed herein. In preferred embodiments, the invention relates to vaccines. In additional embodiments, the invention relates to formulations capable of releasing said vaccines at a controlled rate of release in vivo. In further embodiments, the invention relates to modified strains of the bacteria Brucella melitensis and Brucella abortus. In still further embodiments, the invention relates to compositions that do not induce clinical symptoms or splenomegaly in a subject receiving said compositions.
Ficht, Thomas A.; Ficht, Allison; Tsolis, Renee; Garry Adams, Leslie (2019). Controlled release vaccines and methods of treating Brucella diseases and disorders. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from