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dc.creatorClavijo, Alfonso
dc.creatorRieder, Aida Elizabeth
dc.creatorSayed, Abu
dc.creatorBounpheng, Mangkey A.
dc.creatorBurrage, Thomas G.
dc.creatorDancho, Brooke A.
dc.creatorUddowla Blakeney, Sabena
dc.date.accessioned2019-06-17T17:14:54Z
dc.date.available2019-06-17T17:14:54Z
dc.date.issued2018-07-31
dc.identifier.urihttps://hdl.handle.net/1969.1/177263
dc.description.abstractThis disclosure pertains to isolated antibodies or antigen binding fragments thereof that specifically bind to the 3ABC non-structural protein of Foot-and-Mouth Disease virus (FMDV), wherein the antibodies or antigen binding fragments thereof recognize the amino acid sequence of SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6 or SEQ ID NO: 12. Accordingly, this disclosure also pertains to polypeptides having an amino acid sequence selected from SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5 or SEQ ID NO: 12. Monoclonal antibody Mab 40C8 is also provided. The current disclosure also pertains to methods of detecting FMDV infection in an animal (including assays differentiating infected animals from vaccinated animals (DIVA)) and kits for performing the detection methods. Competitive ELISA kits comprising the antibody or antigen binding fragment thereof and immunoassay plates coated with the polypeptide comprising the amino acid sequence selected from SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6 and/or SEQ ID NO: 12 are also provided.en
dc.languageeng
dc.publisherUnited States. Patent and Trademark Office
dc.rightsPublic Domain (No copyright - United States)en
dc.rights.urihttp://rightsstatements.org/vocab/NoC-US/1.0/
dc.titleMonoclonal antibody against novel epitopes of foot-and-mouth disease virus protein 3ABC and uses thereofen
dc.typeUtility patenten
dc.format.digitalOriginreformatted digitalen
dc.description.countryUS
dc.contributor.assigneeTHE Texas A&M UNIVERSITY SYSTEM
dc.contributor.assigneeTHE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE
dc.contributor.assigneeTHE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF HOMELAND SECURITY
dc.identifier.patentapplicationnumber15/010278
dc.date.filed2016-01-29
dc.publisher.digitalTexas A&M University. Libraries
dc.subject.cpcprimaryC07K 16/1009
dc.subject.cpcprimaryG01N 33/56983
dc.subject.cpcprimaryC07K 2317/34
dc.subject.cpcprimaryC07K 2319/21
dc.subject.cpcprimaryC12N 2770/32122
dc.subject.cpcprimaryC12N 2770/32134
dc.subject.cpcprimaryG01N 2333/09


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