Method of treating inflammatory bowel disease by administering a clip-inducing agent
Abstract
The disclosure relates to methods for treating disorders of the mucosal tract such as the gastrointestinal system by targeting CLIP molecules. The methods are based on that CLIP in the groove of MHC class I or II molecules of the cells lining the mucosal surfaces of the body, such as the gastrointestinal tract, provides protection from MHC Class II or MHC class I mediated cell death, and therefore are useful for treating, inhibiting the development of a multitude of illnesses and conditions of the mucosal tract, including autoimmune disease.
Subject
514/1.1424/85.2
514/21.8
514/44R
A61K 38/1774
A61K 38/08
A61K 38/2026
A61K 38/16
A61K 31/7088
A61K 38/2026
A61K 2300/00
Collections
Citation
Newell, Martha Karen; Harvey, Cassie L.; Tobin, Richard (2014). Method of treating inflammatory bowel disease by administering a clip-inducing agent. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /177088.