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dc.creatorPatti, Joseph M.
dc.creatorFoster, Timothy J.
dc.creatorHook, Magnus
dc.date.accessioned2019-06-17T17:05:38Z
dc.date.available2019-06-17T17:05:38Z
dc.date.issued2011-09-13
dc.identifier.urihttps://hdl.handle.net/1969.1/176960
dc.description.abstractMulticomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies to those proteins or fragments. By careful selection of the proteins, fragments, or antibodies, a vaccine is provided that imparts protection against a broad spectrum of Staphylococcus and other bacterial strains and against proteins that are expressed at different stages of the logarithmic growth curve. In one embodiment of the invention, a composition is provided that includes a fibrinogen binding domain of a fibrinogen binding protein and a bacterial component such as a capsular polysaccharide, and both active and passive vaccines based on these components are also provided, along with methods of treating infection using these compositions and vaccines.en
dc.languageeng
dc.publisherUnited States. Patent and Trademark Office
dc.rightsPublic Domain (No copyright - United States)en
dc.rights.urihttp://rightsstatements.org/vocab/NoC-US/1.0/
dc.titleMulticomponent vaccinesen
dc.typeUtility patenten
dc.format.digitalOriginreformatted digitalen
dc.description.countryUS
dc.contributor.assigneeInhibitex
dc.contributor.assigneeThe Provost Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabeth Near Dublin
dc.contributor.assigneeThe Texas A & M University System
dc.identifier.patentapplicationnumber12/710790
dc.subject.uspcprimary424/243.1
dc.subject.uspcother424/192.1
dc.subject.uspcother424/193.1
dc.subject.uspcother424/197.11
dc.subject.uspcother536/123.1
dc.date.filed2010-02-23
dc.publisher.digitalTexas A&M University. Libraries
dc.subject.cpcprimaryA61K 39/085
dc.subject.cpcprimaryA61P 31/04
dc.subject.cpcprimaryC07K 16/1271


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