Method and system for near-infrared fluorescence contrast-enhanced imaging with area illumination and area detection
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According to one embodiment of the invention, a method for biomedical imaging includes directing time-varying excitation light at a surface area of a light scattering material, the material comprising a fluorescent target. Time-varying emission light from the fluorescent target is detected, substantially at a two-dimensional sensor surface, in response to the time-varying excitation light stimulating the fluorescent target. The time-varying emission light is filtered to reject excitation light re-emitted from the material. A three-dimensional image of the fluorescent target is generated based on the detection substantially at the sensor surface.
Sevick-muraca, Eva M.; Thompson, Alan B.; Ranadhir, Roy (2009). Method and system for near-infrared fluorescence contrast-enhanced imaging with area illumination and area detection. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from