Noninvasive detection of colonic biomarkers using fecal messenger RNA
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A noninvasive method utilizing feces, containing sloughed colonocytes, as a sensitive technique for detecting diagnostic colonic biomarkers as well as a method for isolating poly A +RNA from feces. The method allows the isolation and quantitation of specific eukarotic mRNAs as candidate biomarkers for colon cancer isolated from feces.
Chapkin, Robert S.; Davidson, Laurie A.; Lupton, Joanne R. (2001). Noninvasive detection of colonic biomarkers using fecal messenger RNA. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from