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HSP20 inhibits amyloidogenesis and neurotoxicity
(United States. Patent and Trademark Office, 2014-04-29)
The present invention compositions and methods of using at least a portions of an isolated and purified α-crystallin polypeptide that includes one or more β-pleated sheets and that prevents neurotoxicity and amyloidogenesis.
Designer collagens and use thereof
(United States. Patent and Trademark Office, 2013-12-31)
The present invention identified a recombinant synthetic collagen containing a triple helical backbone protein produced in a prokaryotic expression system where the protein contains at least one ‘inserted’ biologically ...
Treatment of stroke using domain V of perlecan
(United States. Patent and Trademark Office, 2013-06-18)
The present invention is drawn to methods of stimulating or enhancing angiogenesis in a patient comprising, administering to said patient a therapeutically effective amount of an endorepellin protein, wherein said endorepellin ...
Antibodies recognizing a highly expressed putative antigen of CA-MRSA and methods of use
(United States. Patent and Trademark Office, 2012-02-28)
The present invention provides MSCRAMM® proteins from S. aureus which are putative highly-expressed antigens from methicillin-resistant S. aureus, including communit-associated MRSA (CA-MRSA), and these antigens can thus ...
Feline CD86 polypeptides and nucleic acids
(United States. Patent and Trademark Office, 2011-12-06)
The present invention provides isolated and purified DNA encoding feline CD80 (B7-1) ligand, feline CD86 (B7-2) ligand, feline CD28 receptor, or feline CTLA-4 (CD152) receptor, as well as vectors comprising nucleic acid ...
SdrC protein from Staphylococcus aureus and diagnostic kits including same
(United States. Patent and Trademark Office, 2010-10-19)
An isolated extracellular matrix-binding protein, designated as SdrC and its corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or antigenic portions ...
SDRE protein from Staphylococcus aureus and diagnostic kits including same
(United States. Patent and Trademark Office, 2010-12-21)
An isolated extracellular matrix-binding protein, designated as SdrE and its corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or antigenic portions ...
SDRD protein from Staphylococcus aureus and diagnostic kits including same
(United States. Patent and Trademark Office, 2010-11-16)
An isolated extracellular matrix-binding protein, designated as SdrD and its corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or antigenic portions ...
Prokaryotic collagen-like proteins and uses thereof
(United States. Patent and Trademark Office, 2010-04-20)
The present invention provides recombinant triple helical proteins or collagen-like proteins comprising a prokaryotic protein or one or more domains of a prokaryotic protein comprising a collagen-like peptide sequence of ...
Compositions and methods related to toll-like receptor-3
(United States. Patent and Trademark Office, 2011-11-29)
The invention relates to compositions and methods related to Toll-like receptor (TLR) polypeptides. In some embodiments, the invention relates to managing TLR3 related diseases. In further embodiments, the invention relates ...