Browsing by Subject "RNA"
Now showing items 1-19 of 19
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(Texas A&M University. Libraries, 1987)The major objective of this study was to characterize the regions of poly(A) signals, which in addition to the AAUAAA are sufficient for accurate and efficient polyadenylation. In addition, this study was designed to test ...
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(2020-04-13)Tissue engineered 3D cell culture models have shown promise investigating the influence of the tumor microenvironment on cancer cell behavior. Synthetic hydrogels, such as those made from poly(ethylene glycol) (PEG), can ...
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(2009-05-15)MicroRNAs are a large family of 21-26 nucleotide non-coding RNAs with a role in the post-transcriptional regulation of gene expression. In recent years, microRNAs have been proposed to play a significant role in the expansion ...
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(2019-11-12)The nature of Watson – Crick base pairing has enabled the rational design of complex and dynamic DNA/RNA-based molecular circuits capable of detecting nucleic acids in a sequence dependent fashion in vitro. Given the ease ...
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(2020-04-27)This project analyzed the effects of the emerging marine pollutant commonly known as oxybenzone. Oxybenzone is a chemical ingredient commonly used in sunscreen lotions, as well as other hygienic products. There is growing ...
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(Texas A&M University. Libraries, 1977)Immunogenic RNA and normal RNA were obtained by phenol extraction method from peritoneal exudate cells and spleen cells of outbred Swiss Webster and inbred BALB/c mice and the photometric studies were performed. The antigens ...
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(2013-05-16)The innate immune pathways that stimulate the expression of cytokines and proapoptotic factors in response to infection are triggered by the activation of the cytosolic receptors retinoic acid-inducible gene I (RIG-I) and ...
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(Texas A&M University, 2007-04-25)The hammerhead ribozyme (HHRz) catalyzes a site-specific phosphodiester bond cleavage reaction that is enhanced by the presence of metal cations. Metal cations are thought to aid in the folding and possibly the catalytic ...
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(Texas A&M University, 2007-04-25)The function of biomolecules is very sensitive to structure. Folding in proteins and nucleic acids is a hierarchical process progressing from primary to secondary, then tertiary, and finally, quaternary structures. RNA in ...
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(2020-10-09)While transcriptional control of innate immune gene expression is well characterized, almost nothing is known about how pre-mRNA splicing decisions influence, or are influenced by, macrophage activation. I believe each ...
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(2015-11-18)Eukaryotic transcription is a highly regulated process that requires RNA polymerase to continuously proofread and edit the RNA stand before it continues to elongate. A subunit in RNA polymerase II (RNAPII), known as Rpb9, ...
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(Texas A&M University. Libraries, 1992)Sequences at the 5' termini of the genomic RNAs of brome mosaic virus (BMV) and other (+)-stranded RNA viruses have been shown to resemble the internal control regions (ICRs 1 and 2, or A and B boxes) of tRNA genes. In ...
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(Texas A&M University. Libraries, 1988)Polyadenylation of eukaryotic messenger RNA molecules consists of a two step reaction; cleavage of the primary transcript and step-wise addition of adenylic acid residues to the newly generated 3' OH group. The complex ...
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(Texas A&M University, 2005-02-17)Metal-RNA interactions are important to neutralize the negative charge and aid in correctly folding the RNA. Spectroscopically active metal ions, especially Mn2+, have been used to probe the type of interaction the metal ...
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(2012-10-19)RIG-I-like receptors (RLRs), RIG-I, MDA5, and LGP2, are a family of innate immune receptors that recognize viral RNA in the cytoplasm and initiate antiviral responses including the induction of type I interferons and other ...
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(2001)Programmed ribosomal frameshifting is a method of regulation of protein expression in which a change in reading frame during translation brings about the formation of an alternative gene product. This process is an important ...
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(2009-05-15)Most members of the PAS (PER-ARNT-SIM) protein family are transcription factors, mediating development and adaptive responses to the environment, such as circadian rhythms and toxin responses. Because the PAS domain mediates ...
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(Texas A&M University. Libraries, 1977)The research described in this dissertation concerns the isolation of conditional-lethal RNA polymerase mutants of Escherichia coli K-12 that are heat-sensitive for growth. Approaches to specification of mutagenesis to ...
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(Texas A&M University. Libraries, 1982)The biochemical characteristics of the fat body of adult virgin female Blaberus discoidalis were examined during the onset of vitellogenin synthesis. During the first 18-20 days following the final molt to the final form, ...