Browsing by Subject "Circadian"
Now showing items 1-12 of 12
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Cellular and molecular mechanisms that regulate olfactory rhythms in drosophila melanogaster
(2009-05-15)This dissertation is focused on how circadian control of olfactory responses are regulated at the cellular and molecular level in Drosophila. Electrophysiological approaches consisting of Electroantennogram (EAG), single ... -
Characterization of the Molecular Mechanisms Associated with Circadian Clock Control of Transcription
(2018-11-20)The mammalian circadian clock, found in virtually every cell, coordinates rhythmic expression to control the daily regulation of biological functions. These cell autonomous circadian clocks rely on a molecular feedback ... -
Characterizing Novel Circadian Clock Functions for Drosophila Phosphatases and Non-clock Functions for Circadian Photoreceptors
(2016-08-03)Circadian (~24 h) clocks regulate daily cycles in gene expression to control overt rhythms in physiology, metabolism and behavior. In Drosophila, a transcriptional feedback loop activated by CLOCK-CYCLE (CLK-CYC) complexes, ... -
Characterizing the Function of Clockwork Orange in the Circadian Feedback Loops in Drosophila melanogaster
(2017-07-12)The Drosophila circadian oscillator controls daily rhythms in physiology, metabolism and behavior via transcriptional feedback loops. CLOCK-CYCLE (CLK-CYC) heterodimers initiate feedback loop function by binding enhancer ... -
Circadian and Metabolic Control of Macrophage Activation in Obesity
(2016-12-09)Macrophage inflammatory status governs inflammatory responses in metabolic tissues including adipose and liver tissues, and critically contributes to the development of diet-induced obesity and systemic insulin resistance. ... -
Circadian Regulation of L-Type Voltage-Gated Calcium Channels in Avian Retina
(2014-11-25)The circadian clock is an endogenous time-keeping mechanism that allows an organism to synchronize itself with external time cues and prepares the organism to anticipate upcoming environmental changes on a daily basis. The ... -
The hunt for CikR: response regulator for CikA in Synechococcus elongatus PCC 7942
(2006-07-11)Circadian rhythms are daily cycles of activity that have been demonstrated in many organisms including bacteria, fungi, insects, plants, and mammals. A clock system is composed of three parts: the input pathway, the central ... -
MicroRNAs Function as Cis- and Trans- Acting Modulators of Clock Gene Expression in SCN and Peripheral Circadian Oscillators
(2012-11-15)The circadian system in mammals is arranged as a hierarchical network of oscillators, with the master pacemaker of circadian rhythms located in the suprachiasmatic nuclei (SCN) of the hypothalamus and peripheral oscillators ... -
Teasing Apart the Role of the Mammalian Molecular Circadian Clock and Three-Dimensional Chromatin Interactions in Rhythmic Transcription
(2019-10-25)The mammalian molecular circadian clock is composed of a transcriptional-translational feedback loop. The positive arm of this loop is composed of the transcription factor CLOCK:BMAL1 which activates the transcription of ... -
The Mechanism of Glucose Metabolism in Streptozotocin-Induced Diabetic Chicken Embryos
(2013-03-13)The physiological and biochemical processes of the body are regulated by the circadian oscillators, the endogenous biological timing systems. The molecular mechanism of the circadian clock is composed by a specific set ... -
The Stress Response and Circadian Regulation of Translation in Neurospora crassa
(2016-08-01)Stress response pathways function to allow cells to adapt to changes in the environment. In Neurospora crassa, acute osmotic stress activates the conserved p38-like osmosensing mitogen-activated protein kinase (OS MAPK) ... -
The Transcriptional and Translational Response of Neurospora crassa to Salt and Light
(2019-10-17)Many different response-pathways enable microorganisms to respond to changes in the environment. Two environmental conditions that elicit responses in the model filamentous fungus Neurospora crassa are light and osmotic ...