This dissertation is focused on how circadian control of olfactory responses are regulated at the cellular and molecular level in Drosophila. Electrophysiological approaches consisting of Electroantennogram (EAG), single ...

Circadian (~24 h) clocks regulate daily cycles in gene expression to control overt rhythms in physiology, metabolism and behavior. In Drosophila, a transcriptional feedback loop activated by CLOCK-CYCLE (CLK-CYC) complexes, ...

Macrophage inflammatory status governs inflammatory responses in metabolic tissues including adipose and liver tissues, and critically contributes to the development of diet-induced obesity and systemic insulin resistance. ...

Circadian rhythms are daily cycles of activity that have been demonstrated in many organisms including bacteria, fungi, insects, plants, and mammals. A clock system is composed of three parts: the input pathway, the central ...

The physiological and biochemical processes of the body are regulated by the circadian oscillators, the endogenous biological timing systems. The molecular mechanism of the circadian clock is composed by a specific set ...

Stress response pathways function to allow cells to adapt to changes in the environment. In Neurospora crassa, acute osmotic stress activates the conserved p38-like osmosensing mitogen-activated protein kinase (OS MAPK) ...

Many different response-pathways enable microorganisms to respond to changes in the environment. Two environmental conditions that elicit responses in the model filamentous fungus Neurospora crassa are light and osmotic ...