Now showing items 1-16 of 16

    • Collagen binding protein compositions and methods of use 

      Hook, Magnus; Patti, Joseph M.; House-Pompeo, Karen; Sthanam, Narayana; Symersky, Jindrich (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2001-09-11)
      Disclosed are the cna gene and cna-derived nucleic acid segments from Staphylococcus aureus, and DNA segments encoding cna from related bacteria. Also disclosed are Col binding protein (CBP) compositions and methods of ...
    • Collagen-binding proteins from enterococcal bacteria 

      Rich, Rebecca L.; Kriekemeyer, Bernd; Owens, Rick T.; Hook, Magnus; Murray, Barbara E.; Nallapareddy, Sreedhar R.; Weinstock, George M. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2005-06-21)
      A collagen-binding MSCRAMM entitled Ace from enterococcal bacteria is provided which was homologous to the ligand-binding region of Cna, the collagen-binding MSCRAMM from Staphylococcus aureus, and which can be utilized ...
    • Collagen-binding proteins from enterococcal bacteria 

      Rich, Rebecca L.; Kriekemeyer, Bernd; Owens, Rick T.; Hook, Magnus; Murray, Barbara E.; Nallapareddy, Sreedhar R.; Weinstock, George M. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2009-12-29)
      A collagen-binding MSCRAMM entitled Ace from enterococcal bacteria is provided which was homologous to the ligand-binding region of Cna, the collagen-binding MSCRAMM from Staphylococcus aureus, and which can be utilized ...
    • Cross-reactive displacing antibodies from collagen-binding proteins and method of identification and use 

      Hook, Magnus; Xu, Yi; Speziale, Pietro; Visal, Livia; Casolini, Fabrizia; Patti, Joseph M.; Patel, Pratiksha; Domanski, Paul (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2007-07-10)
      Antibodies to the CNA protein and to other regions from the collagen binding domain, including domain CNA19, are provided, and antibodies produced in this manner have been shown to be cross reactive to both Staphylococcus ...
    • Crystal structure of Staphylococcus aureus clumping factor A in complex with fibrinogen derived peptide and uses thereof 

      Hook, Magnus; Ko, Ya-ping; Smeds, Emanuel; Ganesh, Vannakambadi K. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2012-10-02)
      The present invention provides a method for determining the structure of a microbial surface components recognizing adhesive matrix molecule in complex with fibrinogen, by providing a ClfA complexed with a fibrinogen ...
    • Fibronectin binding protein compositions and methods of use 

      Hook, Magnus; Patti, Joseph M.; House-pompeo, Karen L.; Speziale, Pietro; Joh, Danny; Mcgavin, Martin J. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2006-10-31)
      Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...
    • Fibronectin binding protein compositions and methods of use 

      Hook,Magnus; Patti, Joseph M.; House-Pompeo, Karen L.; Speziale, Pietro; Joh, Danny; Mcgavin, Martin J. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2004-02-03)
      Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...
    • Monoclonal antibodies recognizing a coagulase-negative staphylococcal protein 

      Patti, Joseph M.; Hutchins, Jeff T.; Hall, Andrea; Santos, Linda; Bowden, Maria; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2013-07-02)
      Monoclonal antibodies which can bind to the SdrF protein of Staphylococcus epidermidis are provided which can be useful in the treatment and protection against infection from staphylococcal bacteria such as Staphylococcus ...
    • Multicomponent vaccines 

      Patti, Joseph M.; Foster, Timothy J.; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2010-02-23)
      Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies ...
    • Multicomponent vaccines 

      Patti, Joseph M.; Foster, Timothy J.; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2004-03-09)
      Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies ...
    • Multicomponent vaccines 

      Patti, Joseph M.; Foster, Timothy J.; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2011-09-13)
      Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies ...
    • Polypeptides and polynucleotides from coagulase-negative staphylococci 

      Foster, Timothy J.; Mccrea, Kirk; Hook, Magnus A. O.; Davis, Stacey; Ni Eidhin, Deirdre; Hartford, Orla (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2010-05-04)
      Methods for treating or preventing infections from coagulase-negative staphylococci using proteins and polypeptides from coagulase-negative staphylococcal bacteria such as S. epidermidis, including proteins designated SdrF, ...
    • Polypeptides and polynucleotides from coagulase-negative staphylococci 

      Foster, Timothy J.; Mccrea, Kirk; Hook, Magnus A. O.; Davis, Stacy; Ni Eidhin, Deirdre; Hartford, Orla (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2003-10-21)
      Isolated proteins, designated SdrF, SdrG and SdrH, and their corresponding amino acid and nucleic acid sequences are provided which are useful in the prevention and treatment of infection caused by coagulase-negative ...
    • Proteins and polypeptides from coagulaslase-negative staphylococci 

      Foster, Timothy J.; Mccrea, Kirk; Hook, Magnus A. O.; Davis, Stacy; Nieidhin, Deirdre; Hartford, Orla (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2009-01-06)
      Proteins and polypeptides from coagulase-negative staphylococcal bacteria such as S. epidermidis, including proteins designated SdrF, SdrG and SdrH, and their effective fragments such as their respective A domains, are ...
    • Staphylococcal immunotherapeutics via donor selection and donor stimulation 

      Patti, Joseph M.; Foster, Timothy J.; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2004-02-17)
      A method and composition for the passive immunization of patients infected with or susceptible to infection from Staphylococcus bacteria such as S. aureus and S. epidermidis infection is provided that includes the selection ...
    • Treatment of Staphylococcus aureus infections utilizing antibodies that bind to fibronectin binding proteins 

      Hook, Magnus; Patti, Joseph M.; House-pompeo, Karen L.; Speziale, Pietro; Joh, Danny; Mcgavin, Martin J. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2012-07-03)
      Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...